2JUR

alpha RgIA, a Novel Conotoxin that Blocks the alpha9-alpha10 nAChR

Summary for 2JUR

Entry DOI	10.2210/pdb2jur/pdb
Related	2JUQ 2JUS 2JUT
Descriptor	Alpha-conotoxin RgIA (1 entity in total)
Functional Keywords	two-loop backbone architecture, disulfide bond, signaling protein inhibitor, toxin
Cellular location	Secreted (By similarity): P0C1D0
Total number of polymer chains	1
Total formula weight	1592.89
Authors	Feng, Z.,Ellison, M. (deposition date: 2007-09-02, release date: 2011-05-25, Last modification date: 2021-10-20)
Primary citation	Ellison, M.,Feng, Z.P.,Park, A.J.,Zhang, X.,Olivera, B.M.,McIntosh, J.M.,Norton, R.S. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues. J.Mol.Biol., 377:1216-1227, 2008 Cited by PubMed: 18295795 DOI: 10.1016/j.jmb.2008.01.082 PDB entries with the same primary citation
Experimental method	SOLUTION NMR

Structure validation