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1L7A
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structural Genomics, crystal structure of Cephalosporin C deacetylase
Descriptor: Cephalosporin C deacetylase
Authors:Zhang, R, Koroleva, O, Collert, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
Deposit date:2002-03-14
Release date:2003-01-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:1.5A crystal structure of the Cephalosporin C deacetylase
To be Published
4TR7
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BU of 4tr7 by Molmil
Crystal structure of DNA polymerase sliding clamp from Mycobaterium tuberculosis
Descriptor: DNA polymerase III subunit beta
Authors:Olieric, V, Burnouf, D, Ennifar, E, Wolff, P.
Deposit date:2014-06-14
Release date:2014-09-10
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Differential Modes of Peptide Binding onto Replicative Sliding Clamps from Various Bacterial Origins.
J.Med.Chem., 57, 2014
1LDM
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BU of 1ldm by Molmil
Refined crystal structure of dogfish M4 apo-lactate dehydrogenase
Descriptor: M4 LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID
Authors:Griffith, J.P, Rossmann, M.G.
Deposit date:1987-11-25
Release date:1989-07-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined crystal structure of dogfish M4 apo-lactate dehydrogenase.
J.Mol.Biol., 198, 1987
1L83
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A CAVITY-CONTAINING MUTANT OF T4 LYSOZYME IS STABILIZED BY BURIED BENZENE
Descriptor: BENZENE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ...
Authors:Eriksson, A.E, Matthews, B.W.
Deposit date:1992-01-21
Release date:1993-10-31
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene.
Nature, 355, 1992
4TM3
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BU of 4tm3 by Molmil
Kutzneria sp. 744 ornithine N-hydroxylase, KtzI-FADox-Br
Descriptor: BROMIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, KtzI
Authors:Setser, J.W, Drennan, C.L.
Deposit date:2014-05-30
Release date:2014-09-17
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase.
Biochemistry, 53, 2014
3KXT
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BU of 3kxt by Molmil
Crystal structure of Sulfolobus Cren7-dsDNA complex
Descriptor: 5'-D(*GP*CP*GP*AP*TP*CP*GP*C)-3', Chromatin protein Cren7
Authors:Feng, Y, Wang, J.
Deposit date:2009-12-03
Release date:2010-06-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.602 Å)
Cite:Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex
Protein Sci., 19, 2010
1GOO
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BU of 1goo by Molmil
Thermostable xylanase I from Thermoascus aurantiacus - Cryocooled glycerol complex
Descriptor: ENDO-1,4-BETA-XYLANASE, GLYCEROL
Authors:Eckert, K, Andrei, C, Larsen, S, Lo Leggio, L.
Deposit date:2001-10-22
Release date:2001-12-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Substrate Specificity and Subsite Mobility in T. Aurantiacus Xylanase 10A
FEBS Lett., 509, 2001
7Y8F
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BU of 7y8f by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30o and GRIP Peptide
Descriptor: DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ...
Authors:Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T.
Deposit date:2022-06-23
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Eur.J.Med.Chem., 253, 2023
1GRA
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BU of 1gra by Molmil
SUBSTRATE BINDING AND CATALYSIS BY GLUTATHIONE REDUCTASE AS DERIVED FROM REFINED ENZYME: SUBSTRATE CRYSTAL STRUCTURES AT 2 ANGSTROMS RESOLUTION
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, GLUTATHIONE REDUCTASE, ...
Authors:Karplus, P.A, Schulz, G.E.
Deposit date:1992-12-15
Release date:1994-01-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: substrate crystal structures at 2 A resolution.
J.Mol.Biol., 210, 1989
5D9D
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BU of 5d9d by Molmil
Luciferin-regenerating enzyme solved by SAD using synchrotron radiation at room temperature
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Luciferin regenerating enzyme, MAGNESIUM ION, ...
Authors:Yamashita, K, Pan, D, Okuda, T, Murai, T, Kodan, A, Yamaguchi, T, Gomi, K, Kajiyama, N, Kato, H, Ago, H, Yamamoto, M, Nakatsu, T.
Deposit date:2015-08-18
Release date:2015-09-23
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:An isomorphous replacement method for efficient de novo phasing for serial femtosecond crystallography.
Sci Rep, 5, 2015
1H2H
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BU of 1h2h by Molmil
Crystal structure of TM1643
Descriptor: HYPOTHETICAL PROTEIN TM1643, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Yang, Z, Savchenko, A, Edwards, A, Arrowsmith, C, Tong, L, Northeast Structural Genomics Consortium (NESG)
Deposit date:2002-08-08
Release date:2002-08-15
Last modified:2019-08-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Aspartate dehydrogenase, a novel enzyme identified from structural and functional studies of TM1643.
J. Biol. Chem., 278, 2003
7Y6J
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BU of 7y6j by Molmil
Crystal structure of human transthyretin variant A97S at pH 5.4
Descriptor: GLYCEROL, Transthyretin
Authors:Wang, Y.S, Huang, C.H, Tzeng, S.R.
Deposit date:2022-06-20
Release date:2023-05-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7Y8G
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BU of 7y8g by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with an Inhibitor 30a and GRIP Peptide
Descriptor: DI(HYDROXYETHYL)ETHER, Estrogen receptor, Grip peptide, ...
Authors:Min, J, Hu, H.B, Yang, Y, Dong, C.E, Zhou, H.B, Chen, C.-C, Guo, R.-T.
Deposit date:2022-06-23
Release date:2023-04-26
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure-guided identification of novel dual-targeting estrogen receptor alpha degraders with aromatase inhibitory activity for the treatment of endocrine-resistant breast cancer.
Eur.J.Med.Chem., 253, 2023
1XJL
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BU of 1xjl by Molmil
Structure of human annexin A2 in the presence of calcium ions
Descriptor: Annexin A2, CALCIUM ION
Authors:Rosengarth, A, Luecke, H.
Deposit date:2004-09-23
Release date:2004-11-09
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Annexin A2: Does it induce membrane aggregation by a new multimeric state of the protein?
Annexins, 1, 2004
1XJX
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BU of 1xjx by Molmil
The crystal structures of the DNA binding sites of the RUNX1 transcription factor
Descriptor: 5'-D(*TP*CP*TP*GP*CP*GP*GP*TP*C)-3', 5'-D(*TP*GP*AP*CP*CP*GP*CP*AP*G)-3'
Authors:Kitayner, M, Rozenberg, H, Rabinovich, D, Shakked, Z.
Deposit date:2004-09-26
Release date:2005-03-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structures of the DNA-binding site of Runt-domain transcription regulators.
Acta Crystallogr.,Sect.D, 61, 2005
1HL3
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CtBP/BARS in ternary complex with NAD(H) and PIDLSKK peptide
Descriptor: C-TERMINAL BINDING PROTEIN 3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PRO-ILE-ASP-LEU-SER-LYS-LYS PEPTIDE
Authors:Nardini, M, Spano, S, Cericola, C, Pesce, A, Massaro, A, Millo, E, Luini, A, Corda, D, Bolognesi, M.
Deposit date:2003-03-13
Release date:2003-06-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Ctbp/Bars: A Dual-Function Protein Involved in Transcription Co-Repression and Golgi Membrane Fission
Embo J., 22, 2003
1FXV
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BU of 1fxv by Molmil
PENICILLIN ACYLASE MUTANT IMPAIRED IN CATALYSIS WITH PENICILLIN G IN THE ACTIVE SITE
Descriptor: CALCIUM ION, PENICILLIN ACYLASE, PENICILLIN G
Authors:Alkema, W.B, Hensgens, C.M, Kroezinga, E.H, de Vries, E, Floris, R, van der Laan, J.M, Dijkstra, B.W, Janssen, D.B.
Deposit date:2000-09-27
Release date:2001-03-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein Eng., 13, 2000
1XKW
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BU of 1xkw by Molmil
Pyochelin outer membrane receptor FptA from Pseudomonas aeruginosa
Descriptor: 1,2-ETHANEDIOL, Fe(III)-pyochelin receptor, LAURYL DIMETHYLAMINE-N-OXIDE, ...
Authors:Cobessi, D, Celia, H, Pattus, F.
Deposit date:2004-09-30
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure at high resolution of ferric-pyochelin and its membrane receptor FptA from Pseudomonas aeruginosa
J.Mol.Biol., 352, 2005
7YBR
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BU of 7ybr by Molmil
Crystal structure of human transthyretin variant A97S complexed with Tolcapone
Descriptor: Tolcapone, Transthyretin
Authors:Wang, Y.S, Huang, C.H, Tzeng, S.R.
Deposit date:2022-06-29
Release date:2023-05-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
7YCQ
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BU of 7ycq by Molmil
Crystal structure of human transthyretin variant A97S complexed with Diflunisal
Descriptor: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, Transthyretin
Authors:Wang, Y.S, Huang, C.H, Tzeng, S.R.
Deposit date:2022-07-01
Release date:2023-05-03
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser.
Protein Sci., 32, 2023
1FZ3
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BU of 1fz3 by Molmil
METHANE MONOOXYGENASE HYDROXYLASE, FORM III SOAK AT PH 6.2 (0.1 M PIPES)
Descriptor: CALCIUM ION, FE (III) ION, FORMIC ACID, ...
Authors:Whittington, D.A, Lippard, S.J.
Deposit date:2000-10-03
Release date:2001-02-21
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site.
J.Am.Chem.Soc., 123, 2001
1FWE
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BU of 1fwe by Molmil
KLEBSIELLA AEROGENES UREASE, C319A VARIANT WITH ACETOHYDROXAMIC ACID (AHA) BOUND
Descriptor: ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997
4G04
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BU of 4g04 by Molmil
High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
Descriptor: Serum albumin
Authors:Cao, H.L, Yin, D.C.
Deposit date:2012-07-09
Release date:2013-07-10
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:High-resolution Crystal Structural Variance Analysis between Recombinant and Wild-type Human Serum Albumin
To be Published
2ZO2
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BU of 2zo2 by Molmil
Mouse NP95 SRA domain non-specific DNA complex
Descriptor: DNA (5'-D(*DAP*DAP*DCP*DTP*DGP*DCP*DGP*DCP*DAP*DGP*DTP*DT)-3'), E3 ubiquitin-protein ligase UHRF1, PHOSPHATE ION
Authors:Hashimoto, H, Horton, J.R, Cheng, X.
Deposit date:2008-05-05
Release date:2008-09-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix
Nature, 455, 2008
1FWD
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KLEBSIELLA AEROGENES UREASE, C319A VARIANT AT PH 9.4
Descriptor: NICKEL (II) ION, UREASE
Authors:Pearson, M.A, Karplus, P.A.
Deposit date:1997-04-23
Release date:1997-10-15
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Cys319 variants and acetohydroxamate-inhibited Klebsiella aerogenes urease.
Biochemistry, 36, 1997

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