7YCQ
Crystal structure of human transthyretin variant A97S complexed with Diflunisal
Summary for 7YCQ
Entry DOI | 10.2210/pdb7ycq/pdb |
Descriptor | Transthyretin, 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID (3 entities in total) |
Functional Keywords | transport thyroxine, transport protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 28087.12 |
Authors | Wang, Y.S.,Huang, C.H.,Tzeng, S.R. (deposition date: 2022-07-01, release date: 2023-05-03, Last modification date: 2024-05-29) |
Primary citation | Wang, Y.S.,Huang, C.H.,Liou, G.G.,Hsueh, H.W.,Liang, C.T.,Tseng, H.C.,Huang, S.J.,Chao, C.C.,Hsieh, S.T.,Tzeng, S.R. A molecular basis for tetramer destabilization and aggregation of transthyretin Ala97Ser. Protein Sci., 32:e4610-e4610, 2023 Cited by PubMed: 36851846DOI: 10.1002/pro.4610 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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