7YCQ
Crystal structure of human transthyretin variant A97S complexed with Diflunisal
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Transthyretin | polymer | 127 | 13793.4 | 2 | UniProt (P02766) Pfam (PF00576) In PDB | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | A, B | 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID | non-polymer | 250.2 | 2 | Chemie (1FL) | |||
| 3 | water | water | 18.0 | 97 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Ser 97 | Ala 117 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27586.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 500.4 | |
| All* | Total formula weight | 28087.1 |
