8VJY
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6XPH
| CutR dimer with domain swap | Descriptor: | Ethanolamine utilization protein EutS, GLYCEROL, POTASSIUM ION, ... | Authors: | Ochoa, J.M, Sawaya, M.R, Nguyen, V.N, Duilio, C, Yeates, T.O, Nie, M. | Deposit date: | 2020-07-08 | Release date: | 2020-07-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization. Protein Sci., 29, 2020
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4KN0
| Human folate receptor beta (FOLR2) in complex with the antifolate methotrexate | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Folate receptor beta, ... | Authors: | Wibowo, A.S, Dann III, C.E. | Deposit date: | 2013-05-08 | Release date: | 2013-08-07 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition. Proc.Natl.Acad.Sci.USA, 110, 2013
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7SCI
| AM0627 metallopeptidase from Akkermansia muciniphila | Descriptor: | CHLORIDE ION, FORMIC ACID, Peptidase M60 domain-containing protein, ... | Authors: | Fernandez, D, Bertozzi, C.R, Shon, D.J. | Deposit date: | 2021-09-28 | Release date: | 2022-04-27 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J.Biol.Chem., 298, 2022
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7AD7
| Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide. | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R. | Deposit date: | 2020-09-14 | Release date: | 2021-03-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The allosteric modulation of Complement C5 by knob domain peptides. Elife, 10, 2021
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1N1M
| Human Dipeptidyl Peptidase IV/CD26 in complex with an inhibitor | Descriptor: | 2-AMINO-3-METHYL-1-PYRROLIDIN-1-YL-BUTAN-1-ONE, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Rasmussen, H.B, Branner, S, Wiberg, F.C, Wagtmann, N.R. | Deposit date: | 2002-10-18 | Release date: | 2002-12-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analogue Nat.Struct.Biol., 10, 2003
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6XPK
| CutR Screw, form 1 with 41.9 angstrom pitch | Descriptor: | Ethanolamine utilization protein EutS | Authors: | Ochoa, J.M, Sawaya, M.R, Nguyen, V.N, Duilio, C, Yeates, T.O. | Deposit date: | 2020-07-08 | Release date: | 2020-07-22 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization. Protein Sci., 29, 2020
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6X6H
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8UZT
| Mitochondrial single-stranded binding protein bound to DNA | Descriptor: | GLYCEROL, SODIUM ION, Single-stranded DNA-binding protein, ... | Authors: | Riccio, A.A, Pedersen, L.C, Bouvette, J, Borgnia, J.M, Copeland, W.C. | Deposit date: | 2023-11-16 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of the mitochondrial single-stranded DNA binding protein with DNA and DNA polymerase gamma. Nucleic Acids Res., 2024
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6HKU
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3L35
| PIE12 D-peptide against HIV entry | Descriptor: | GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 | Authors: | Welch, B.D, Redman, J.S, Paul, S, Whitby, F.G, Weinstock, M.T, Reeves, J.D, Lie, Y.S, Eckert, D.M, Hill, C.P, Root, M.J, Kay, M.S. | Deposit date: | 2009-12-16 | Release date: | 2010-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J.Virol., 84, 2010
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8WQ5
| Crystal structure of the C-terminal RRM domain of an RBP in complex with ssDNA | Descriptor: | DNA (5'-D(*GP*AP*CP*GP*CP*AP*G)-3'), GLYCEROL, RNA-binding protein 45 | Authors: | Chen, X, Yang, Z, Chen, X, Wei, Q, Guo, S, Jiang, M, Wang, M. | Deposit date: | 2023-10-11 | Release date: | 2024-08-21 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural basis for RNA recognition by the C-terminal RRM domain of human RBM45. J.Biol.Chem., 2024
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7RX2
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7C5Z
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5CXF
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7RXH
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7RX3
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7RXG
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9CHQ
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9CHS
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9CHR
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8TZQ
| CryoEM structure of D2 dopamine receptor in complex with GoA KE Mutant, scFv16, and dopamine | Descriptor: | D(2) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Krumm, B.E, Kapolka, N.J, Fay, J.F, Roth, B.L. | Deposit date: | 2023-08-27 | Release date: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state. Nat Commun, 15, 2024
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6XU1
| Crystal structure of tetrameric human H215A-SAMHD1 (residues 109-626) with GTP, dAMPNPP and Mg | Descriptor: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, FE (III) ION, ... | Authors: | Morris, E.R, Kunzelmann, S, Caswell, S.J, Arnold, L.H, Purkiss, A.G, Kelly, G, Taylor, I.A. | Deposit date: | 2020-01-17 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis. Nat Commun, 11, 2020
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9IJE
| Epinephrine-activated human beta3 adrenergic receptor | Descriptor: | Beta-3 adrenergic receptor, Camelid antibody VHH fragment, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | Deposit date: | 2024-06-22 | Release date: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker. Chempluschem, 2024
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9IJD
| Carazolol-activated human beta3 adrenergic receptor | Descriptor: | (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, Beta-3 adrenergic receptor, Camelid antibody VHH fragment, ... | Authors: | Zheng, S, Zhang, S, Dai, S, Chen, K, Gao, K, Lin, B, Liu, X. | Deposit date: | 2024-06-22 | Release date: | 2024-08-21 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Molecular Mechanism of the beta 3AR Agonist Activity of a beta-Blocker. Chempluschem, 2024
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