7AD7

Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.

Summary for 7AD7

Entry DOI	10.2210/pdb7ad7/pdb
Descriptor	Complement C5, K8 peptide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
Functional Keywords	complement c5, c5, ultralong, ultra-long, knob domain., immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	384305.19
Authors	Macpherson, A.,van den Elsen, J.M.H.,Schulze, M.E.,Birtley, J.R. (deposition date: 2020-09-14, release date: 2021-03-10, Last modification date: 2024-01-31)
Primary citation	Macpherson, A.,Laabei, M.,Ahdash, Z.,Graewert, M.A.,Birtley, J.R.,Schulze, M.E.,Crennell, S.,Robinson, S.A.,Holmes, B.,Oleinikovas, V.,Nilsson, P.H.,Snowden, J.,Ellis, V.,Mollnes, T.E.,Deane, C.M.,Svergun, D.,Lawson, A.D.,van den Elsen, J.M. The allosteric modulation of Complement C5 by knob domain peptides. Elife, 10:-, 2021 Cited by PubMed: 33570492 DOI: 10.7554/eLife.63586 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation