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7AD7

Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Complement C5polymer1676188512.12UniProt (P01031)
Pfam (PF17790)
Pfam (PF07677)
Pfam (PF01759)
Pfam (PF01835)
Pfam (PF17791)
Pfam (PF17789)
Pfam (PF07703)
Pfam (PF01821)
Pfam (PF00207)
Pfam (PF07678)
Pfam (PF21309)
Homo sapiens (Human)C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
2C
(C)
K8 peptidepolymer525961.51Bos taurus
3D
(D)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
4E, F, H, L
(B, A, C)
ETHANOLnon-polymer46.14Chemie (EOH)
5G
(B)
(CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACIDnon-polymer190.21Chemie (MHA)
6I, J
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.22Chemie (MPD)
7K
(A)
CYSTEINEnon-polymer121.21Chemie (CYS)
8M
(C)
TRIS(HYDROXYETHYL)AMINOMETHANEnon-polymer163.21Chemie (TAM)
9N, O, P
(B, A, C)
waterwater18.0402Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight382985.6
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules9
Total formula weight895.1
All*Total formula weight384305.2
*Water molecules are not included.

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PDB entries from 2025-06-18

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