7AD7
Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (B, A) | Complement C5 | polymer | 1676 | 188512.1 | 2 | UniProt (P01031) Pfam (PF17790) Pfam (PF07677) Pfam (PF01759) Pfam (PF01835) Pfam (PF17791) Pfam (PF17789) Pfam (PF07703) Pfam (PF01821) Pfam (PF00207) Pfam (PF07678) Pfam (PF21309) | Homo sapiens (Human) | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 |
2 | C (C) | K8 peptide | polymer | 52 | 5961.5 | 1 | Bos taurus | ||
3 | D (D) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
4 | E, F, H, L (B, A, C) | ETHANOL | non-polymer | 46.1 | 4 | Chemie (EOH) | |||
5 | G (B) | (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID | non-polymer | 190.2 | 1 | Chemie (MHA) | |||
6 | I, J (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 2 | Chemie (MPD) | |||
7 | K (A) | CYSTEINE | non-polymer | 121.2 | 1 | Chemie (CYS) | |||
8 | M (C) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 1 | Chemie (TAM) | |||
9 | N, O, P (B, A, C) | water | water | 18.0 | 402 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 382985.6 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 895.1 | |
All* | Total formula weight | 384305.2 |