3L35

PIE12 D-peptide against HIV entry

Summary for 3L35

Entry DOI	10.2210/pdb3l35/pdb
Related	2R5D 3L35 3L36
Descriptor	GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 (3 entities in total)
Functional Keywords	coiled-coil, d-peptide inhibitor, de novo protein
Total number of polymer chains	6
Total formula weight	22487.63
Authors	Welch, B.D.,Redman, J.S.,Paul, S.,Whitby, F.G.,Weinstock, M.T.,Reeves, J.D.,Lie, Y.S.,Eckert, D.M.,Hill, C.P.,Root, M.J.,Kay, M.S. (deposition date: 2009-12-16, release date: 2010-11-03, Last modification date: 2011-07-13)
Primary citation	Welch, B.D.,Francis, J.N.,Redman, J.S.,Paul, S.,Weinstock, M.T.,Reeves, J.D.,Lie, Y.S.,Whitby, F.G.,Eckert, D.M.,Hill, C.P.,Root, M.J.,Kay, M.S. Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J.Virol., 84:11235-11244, 2010 Cited by PubMed: 20719956 DOI: 10.1128/JVI.01339-10 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation