7SCI
AM0627 metallopeptidase from Akkermansia muciniphila
Summary for 7SCI
| Entry DOI | 10.2210/pdb7sci/pdb |
| Descriptor | Peptidase M60 domain-containing protein, ZINC ION, TRIETHYLENE GLYCOL, ... (6 entities in total) |
| Functional Keywords | metalloenzyme, o-glycoprotease, mucinase, hydrolase |
| Biological source | Akkermansia muciniphila (strain ATCC BAA-835 / DSM 22959 / JCM 33894 / BCRC 81048 / CCUG 64013 / CIP 107961 / Muc) |
| Total number of polymer chains | 1 |
| Total formula weight | 55930.88 |
| Authors | Fernandez, D.,Bertozzi, C.R.,Shon, D.J. (deposition date: 2021-09-28, release date: 2022-04-27, Last modification date: 2023-10-18) |
| Primary citation | Shon, D.J.,Fernandez, D.,Riley, N.M.,Ferracane, M.J.,Bertozzi, C.R. Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences. J.Biol.Chem., 298:101917-101917, 2022 Cited by PubMed: 35405095DOI: 10.1016/j.jbc.2022.101917 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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