5ZY8
| Crystal structure of C terminal truncated HadBC (3R-Hydroxyacyl-ACP Dehydratase) complex from Mycobacterium tuberculosis | Descriptor: | 3-hydroxyacyl-ACP dehydratase, UPF0336 protein Rv0637 | Authors: | Singh, B.K, Biswas, R, Bhattacharyya, S, Basak, A, Das, A.K. | Deposit date: | 2018-05-23 | Release date: | 2019-06-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.899 Å) | Cite: | The C-terminal end of mycobacterial HadBC regulates AcpM interaction during the FAS-II pathway: a structural perspective. Febs J., 2022
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7KL8
| Structure of F420 binding protein Rv1558 from Mycobacterium tuberculosis with F420 bound | Descriptor: | COENZYME F420, COENZYME F420-3, Deazaflavin-dependent nitroreductase, ... | Authors: | Lee, B.M, Tan, L.L, Jackson, C.J. | Deposit date: | 2020-10-29 | Release date: | 2021-03-24 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.469 Å) | Cite: | Potency boost of a Mycobacterium tuberculosis dihydrofolate reductase inhibitor by multienzyme F 420 H 2 -dependent reduction. Proc.Natl.Acad.Sci.USA, 118, 2021
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5ZS6
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5ZUL
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7WWF
| Crystal structure of BioH3 from Mycolicibacterium smegmatis | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | Authors: | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | Deposit date: | 2022-02-12 | Release date: | 2022-07-06 | Last modified: | 2023-01-18 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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5Z3R
| Crystal Structure of Delta 5-3-Ketosteroid Isomerase from Mycobacterium sp. | Descriptor: | Steroid delta-isomerase | Authors: | Cheng, X.Y, Peng, F, Yang, F, Huang, Y.Q, Su, Z.D. | Deposit date: | 2018-01-08 | Release date: | 2018-01-31 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Structure-based reconstruction of a Mycobacterium hypothetical protein into an active Delta5-3-ketosteroid isomerase. Biochim Biophys Acta Proteins Proteom, 1867, 2019
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6AYU
| Crystal structure of fructose-1,6-bisphosphatase T84S from Mycobacterium tuberculosis | Descriptor: | 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class 2, GLYCEROL, ... | Authors: | Abad-Zapatero, C, Wolf, N, Gutka, H.J, Movahedzadeh, F. | Deposit date: | 2017-09-08 | Release date: | 2018-03-14 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of the Mycobacterium tuberculosis GlpX protein (class II fructose-1,6-bisphosphatase): implications for the active oligomeric state, catalytic mechanism and citrate inhibition. Acta Crystallogr D Struct Biol, 74, 2018
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4KN4
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4KN7
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7TEF
| Cytochrome P450 14 alpha-sterol demethylase CYP51 from Mycobacterium marinum | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450 51B1 Cyp51B1, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Mohamed, H.A, Bruning, J.B, Bell, S.G. | Deposit date: | 2022-01-04 | Release date: | 2022-11-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | A comparison of the bacterial CYP51 cytochrome P450 enzymes from Mycobacterium marinum and Mycobacterium tuberculosis. J.Steroid Biochem.Mol.Biol., 221, 2022
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6A4L
| AcrR from Mycobacterium tuberculosis | Descriptor: | SODIUM ION, SULFATE ION, TetR family transcriptional regulator | Authors: | Kang, S.M. | Deposit date: | 2018-06-20 | Release date: | 2019-06-26 | Last modified: | 2020-04-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism. Febs Open Bio, 9, 2019
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6A4W
| AcrR from Mycobacterium tuberculosis | Descriptor: | GLYCEROL, SODIUM ION, SULFATE ION, ... | Authors: | Kang, S.M, Kim, D.H. | Deposit date: | 2018-06-21 | Release date: | 2019-06-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.587 Å) | Cite: | The crystal structure of AcrR from Mycobacterium tuberculosis reveals a one-component transcriptional regulation mechanism. Febs Open Bio, 9, 2019
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7UK4
| KS-AT di-domain of mycobacterial Pks13 with endogenous KS ligand bound | Descriptor: | Polyketide synthase PKS13, UNKNOWN LIGAND | Authors: | Kim, S.K, Dickinson, M.S, Finer-Moore, J.S, Rosenberg, O.S, Stroud, R.M. | Deposit date: | 2022-03-31 | Release date: | 2023-02-15 | Last modified: | 2023-03-29 | Method: | ELECTRON MICROSCOPY (1.94 Å) | Cite: | Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13. Nat.Struct.Mol.Biol., 30, 2023
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7VMX
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5YTZ
| Crystal structure of echinomycin-d(ACGTCGT)2 complex | Descriptor: | 2-CARBOXYQUINOXALINE, DNA (5'-D(P*AP*CP*GP*TP*CP*GP*(UD))-3'), Echinomycin, ... | Authors: | Hou, M.H, Wu, P.C, Kao, Y.F. | Deposit date: | 2017-11-20 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Cooperative recognition of T:T mismatch by echinomycin causes structural distortions in DNA duplex Nucleic Acids Res., 46, 2018
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7U0M
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7TLO
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7VOK
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8IBU
| Cryo-EM structure of the erythromycin-bound motilin receptor-Gq protein complex | Descriptor: | ERYTHROMYCIN A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | You, C, Jiang, Y, Xu, H.E, Xu, Y. | Deposit date: | 2023-02-10 | Release date: | 2023-04-12 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.51 Å) | Cite: | Structural basis for motilin and erythromycin recognition by motilin receptor. Sci Adv, 9, 2023
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7VO0
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7VO9
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3H0G
| RNA Polymerase II from Schizosaccharomyces pombe | Descriptor: | DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Spahr, H, Calero, G, Bushnell, D.A, Kornberg, R.D. | Deposit date: | 2009-04-09 | Release date: | 2009-08-25 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Schizosacharomyces pombe RNA polymerase II at 3.6-A resolution. Proc.Natl.Acad.Sci.USA, 106, 2009
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7PIB
| 70S ribosome with EF-G, A/P- and P/E-site tRNAs in spectinomycin-treated Mycoplasma pneumoniae cells | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Xue, L, Lenz, S, Rappsilber, J, Mahamid, J. | Deposit date: | 2021-08-19 | Release date: | 2022-05-25 | Last modified: | 2022-10-19 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | Visualizing translation dynamics at atomic detail inside a bacterial cell. Nature, 610, 2022
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1AO4
| COBALT(III)-PEPLOMYCIN COMPLEX DETERMINED BY NMR STUDIES | Descriptor: | 3-O-carbamoyl-alpha-D-mannopyranose-(1-2)-alpha-L-gulopyranose, AGLYCON OF PEPLOMYCIN, COBALT (III) ION, ... | Authors: | Caceres-Cortes, J, Sugiyama, H, Ikudome, K, Saito, I, Wang, A.H.-J. | Deposit date: | 1997-07-16 | Release date: | 1999-07-30 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structures of cobalt(III)-pepleomycin and cobalt(III)-deglycopepleomycin (green forms) determined by NMR studies. Eur.J.Biochem., 244, 1997
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1AO1
| INTERACTIONS OF DEGLYCOSYLATED COBALT(III)-PEPLEOMYCIN WITH DNA, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | COBALT (III)-DEGLYCOPEPLEOMYCIN, DNA (5'-D(*CP*GP*TP*AP*CP*G)-3') | Authors: | Caceres-Cortes, J, Sugiyama, H, Ikudome, K, Saito, I, Wang, A.H.-J. | Deposit date: | 1997-07-16 | Release date: | 1997-09-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Interactions of deglycosylated cobalt(III)-pepleomycin (green form) with DNA based on NMR structural studies,. Biochemistry, 36, 1997
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