4KN7

X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Benzoxazinorifamycin-2c

Summary for 4KN7

• Entry DOI: 10.2210/pdb4kn7/pdb
• Related: 4KMU 4KN4
• Descriptor: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... (8 entities in total)
• Functional Keywords: transcription, dna, rna, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Escherichia coli; More
• Total number of polymer chains: 12
• Total formula weight: 922194.23

Authors

Murakami, K.S. (deposition date: 2013-05-08, release date: 2013-05-22, Last modification date: 2023-09-20)

• Primary citation: Molodtsov, V.,Nawarathne, I.N.,Scharf, N.T.,Kirchhoff, P.D.,Showalter, H.D.,Garcia, G.A.,Murakami, K.S.; X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.; J.Med.Chem., 56:4758-4763, 2013; PubMed: 23679862; DOI: 10.1021/jm4004889

Experimental method

X-RAY DIFFRACTION (3.686 Å)