2P6X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2p6x by Molmil](/molmil-images/mine/2p6x) | Crystal structure of human tyrosine phosphatase PTPN22 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Ugochukwu, E, Salah, E, Barr, A, Shrestha, L, Alfano, I, Burgess-Brown, N, King, O, Umeano, C, Papagrigoriou, E, Pike, A.C.W, Bunkoczi, G, Turnbull, A, Uppenberg, J, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2007-03-19 | Release date: | 2007-04-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136, 2009
|
|
7AAM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7aam by Molmil](/molmil-images/mine/7aam) | Crystal structure of the F-BAR domain of PSTIPIP1 bound to the CTH domain of the phosphatase LYP | Descriptor: | GLYCEROL, Proline-serine-threonine phosphatase-interacting protein 1, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Manso, J.A, Alcon, P, Bayon, Y, Alonso, A, de Pereda, J.M. | Deposit date: | 2020-09-04 | Release date: | 2022-02-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Cell.Mol.Life Sci., 79, 2022
|
|
3H2X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3h2x by Molmil](/molmil-images/mine/3h2x) | |
3BRH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3brh by Molmil](/molmil-images/mine/3brh) | |
4J51
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4j51 by Molmil](/molmil-images/mine/4j51) | |
3OLR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3olr by Molmil](/molmil-images/mine/3olr) | |
2QCT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qct by Molmil](/molmil-images/mine/2qct) | Structure of Lyp with inhibitor I-C11 | Descriptor: | 1,2-ETHANEDIOL, 6-HYDROXY-3-{(4R)-1-[4-(1-NAPHTHYLAMINO)-4-OXOBUTYL]-1,2,3-TRIAZOLIDIN-4-YL}-1-BENZOFURAN-5-CARBOXYLIC ACID, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Yu, X, Sun, J.P, Zhang, Z.Y. | Deposit date: | 2007-06-19 | Release date: | 2007-11-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of Lyp and its complex with a selective inhibitor To be Published
|
|
3OMH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3omh by Molmil](/molmil-images/mine/3omh) | Crystal structure of PTPN22 in complex with SKAP-HOM pTyr75 peptide | Descriptor: | Src kinase-associated phosphoprotein 2, Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Yu, X, Sun, J.-P, Zhang, S, Zhang, Z.-Y. | Deposit date: | 2010-08-26 | Release date: | 2011-06-29 | Last modified: | 2011-09-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Substrate Specificity of Lymphoid-specific Tyrosine Phosphatase (Lyp) and Identification of Src Kinase-associated Protein of 55 kDa Homolog (SKAP-HOM) as a Lyp Substrate. J.Biol.Chem., 286, 2011
|
|
2QCJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qcj by Molmil](/molmil-images/mine/2qcj) | Native Structure of Lyp | Descriptor: | Tyrosine-protein phosphatase non-receptor type 22 | Authors: | Sun, J.P, Yu, X, Zhang, Z.Y. | Deposit date: | 2007-06-19 | Release date: | 2007-11-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of Lyp and its complex with a selective inhibitor To be Published
|
|