7AAM

Crystal structure of the F-BAR domain of PSTIPIP1 bound to the CTH domain of the phosphatase LYP

Summary for 7AAM

Entry DOI	10.2210/pdb7aam/pdb
Related	7AAL 7AAN
Descriptor	Proline-serine-threonine phosphatase-interacting protein 1, Tyrosine-protein phosphatase non-receptor type 22, GLYCEROL, ... (4 entities in total)
Functional Keywords	pyogenic arthritis, pyoderma gangrenosum and acne (papa), inflammatory response, membrane binding, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	71090.97
Authors	Manso, J.A.,Alcon, P.,Bayon, Y.,Alonso, A.,de Pereda, J.M. (deposition date: 2020-09-04, release date: 2022-02-23, Last modification date: 2024-02-07)
Primary citation	Manso, J.A.,Marcos, T.,Ruiz-Martin, V.,Casas, J.,Alcon, P.,Sanchez Crespo, M.,Bayon, Y.,de Pereda, J.M.,Alonso, A. PSTPIP1-LYP phosphatase interaction: structural basis and implications for autoinflammatory disorders. Cell.Mol.Life Sci., 79:131-131, 2022 Cited by PubMed: 35152348 DOI: 10.1007/s00018-022-04173-w PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation