2P6X
Crystal structure of human tyrosine phosphatase PTPN22
Summary for 2P6X
Entry DOI | 10.2210/pdb2p6x/pdb |
Related | 2OC3 |
Descriptor | Tyrosine-protein phosphatase non-receptor type 22, 1,2-ETHANEDIOL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | tyrosine phosphatase, lymphoid phosphatase, pep, lyp, structural genomics, structural genomics consortium, sgc, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : Q9Y2R2 |
Total number of polymer chains | 2 |
Total formula weight | 73313.40 |
Authors | Ugochukwu, E.,Salah, E.,Barr, A.,Shrestha, L.,Alfano, I.,Burgess-Brown, N.,King, O.,Umeano, C.,Papagrigoriou, E.,Pike, A.C.W.,Bunkoczi, G.,Turnbull, A.,Uppenberg, J.,Sundstrom, M.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,von Delft, F.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2007-03-19, release date: 2007-04-03, Last modification date: 2023-08-30) |
Primary citation | Barr, A.J.,Ugochukwu, E.,Lee, W.H.,King, O.N.,Filippakopoulos, P.,Alfano, I.,Savitsky, P.,Burgess-Brown, N.A.,Muller, S.,Knapp, S. Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136:352-363, 2009 Cited by PubMed: 19167335DOI: 10.1016/j.cell.2008.11.038 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report