3H2X
Crystal Structure of The Human Lymphoid Tyrosine Phosphatase Catalytic Domain
Summary for 3H2X
| Entry DOI | 10.2210/pdb3h2x/pdb |
| Descriptor | Tyrosine-protein phosphatase non-receptor type 22, PHOSPHATE ION (3 entities in total) |
| Functional Keywords | sh2-like fold, alternative splicing, cytoplasm, hydrolase, polymorphism, protein phosphatase, systemic lupus erythematosus |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm (By similarity): Q9Y2R2 |
| Total number of polymer chains | 1 |
| Total formula weight | 36089.75 |
| Authors | Tsai, S.J.,Sen, U. (deposition date: 2009-04-14, release date: 2009-06-02, Last modification date: 2023-09-06) |
| Primary citation | Tsai, S.J.,Sen, U.,Zhao, L.,Greenleaf, W.B.,Dasgupta, J.,Fiorillo, E.,Orru, V.,Bottini, N.,Chen, X.S. Crystal structure of the human lymphoid tyrosine phosphatase catalytic domain: insights into redox regulation . Biochemistry, 48:4838-4845, 2009 Cited by PubMed: 19371084DOI: 10.1021/bi900166y PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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