2E32
 
 | | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | | Descriptor: | F-box only protein 2, S-phase kinase-associated protein 1A | | Authors: | Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. | | Deposit date: | 2006-11-20 | | Release date: | 2007-03-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (3.52 Å) | | Cite: | Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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7Z8B
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2E31
 | | Structural basis for selection of glycosylated substrate by SCFFbs1 ubiquitin ligase | | Descriptor: | F-box only protein 2, S-phase kinase-associated protein 1A | | Authors: | Mizushima, T, Yoshida, Y, Kumanomidou, T, Hasegawa, Y, Yamane, T, Tanaka, K. | | Deposit date: | 2006-11-20 | | Release date: | 2007-03-20 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for the selection of glycosylated substrates by SCFFbs1 ubiquitin ligase
Proc.Natl.Acad.Sci.Usa, 104, 2007
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8S7D
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8S7E
 | | Cryo-EM structure of SKP1-FBXO22 | | Descriptor: | F-box only protein 22, S-phase kinase-associated protein 1 | | Authors: | Khoshouei, M. | | Deposit date: | 2024-02-29 | | Release date: | 2024-12-11 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structure of SKP1-FBXO22 at 3.4A resolution
To Be Published
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8UA6
 | | Cryo-EM Structure of SCF-FBOX22-BACH1BTB | | Descriptor: | Cullin-1, F-box only protein 22, S-phase kinase-associated protein 1, ... | | Authors: | Shi, H, Cao, S, Zheng, N. | | Deposit date: | 2023-09-20 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.
Cell, 187, 2024
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8UA3
 | | Cryo-EM Structure of FBOX22-BACH1BTB | | Descriptor: | F-box only protein 22, Transcription regulator protein BACH1 | | Authors: | Shi, H, Cao, S, Zheng, N. | | Deposit date: | 2023-09-20 | | Release date: | 2024-11-06 | | Last modified: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress.
Cell, 187, 2024
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3L2O
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3C6N
 | | Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling | | Descriptor: | (2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | | Authors: | Tan, X, Zheng, N, Hayashi, K. | | Deposit date: | 2008-02-04 | | Release date: | 2008-04-22 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C6P
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3C6O
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9JKB
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9KBF
 | | Cryo-EM structure of the SKP1-FBXO3 complex | | Descriptor: | F-box only protein 3, S-phase kinase-associated protein 1 | | Authors: | Wei, J, Xu, C. | | Deposit date: | 2024-10-30 | | Release date: | 2025-02-19 | | Last modified: | 2025-02-26 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structural Insight Into the SKP1-CUL1-FBXO3-RBX1 Complex.
Proteins, 2025
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9KBD
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2P1P
 | | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, ... | | Authors: | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
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2P1N
 | | Mechanism of Auxin Perception by the TIR1 Ubiqutin Ligase | | Descriptor: | (2,4-DICHLOROPHENOXY)ACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, C, Zheng, N. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
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2P1O
 | | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | | Descriptor: | Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, NAPHTHALEN-1-YL-ACETIC ACID, ... | | Authors: | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
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2P1M
 | | TIR1-ASK1 complex structure | | Descriptor: | INOSITOL HEXAKISPHOSPHATE, SKP1-like protein 1A, TRANSPORT INHIBITOR RESPONSE 1 protein | | Authors: | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | | Deposit date: | 2007-03-05 | | Release date: | 2007-04-10 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanism of auxin perception by the TIR1 ubiquitin ligase
Nature, 446, 2007
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2P1Q
 | | Mechanism of Auxin Perception by the TIR1 ubiquitin ligase | | Descriptor: | 1H-INDOL-3-YLACETIC ACID, Auxin-responsive protein IAA7, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Tan, X, Calderon-Villalobos, L.I.A, Sharon, M, Robinson, C.V, Estelle, M, Zheng, N. | | Deposit date: | 2007-03-06 | | Release date: | 2007-04-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Mechanism of auxin perception by the TIR1 ubiquitin ligase.
Nature, 446, 2007
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6O60
 | | Crystal structure of GGTase3-FBXL2-SKP1 complex | | Descriptor: | F-box/LRR-repeat protein 2, Geranylgeranyl transferase type-2 subunit beta, Protein prenyltransferase alpha subunit repeat-containing protein 1, ... | | Authors: | Wang, H, Zheng, N. | | Deposit date: | 2019-03-04 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.
Nat.Struct.Mol.Biol., 26, 2019
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1NEX
 | | Crystal Structure of ScSkp1-ScCdc4-CPD peptide complex | | Descriptor: | CDC4 protein, Centromere DNA-binding protein complex CBF3 subunit D, GLL(TPO)PPQSG | | Authors: | Orlicky, S, Tang, X, Willems, A, Tyers, M, Sicheri, F. | | Deposit date: | 2002-12-12 | | Release date: | 2003-02-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis for Phosphodependent Substrate Selection and
Orientation by the SCFCdc4 Ubiquitin Ligase
Cell(Cambridge,Mass.), 112, 2003
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3V7D
 | | Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex | | Descriptor: | Cell division control protein 4, Protein SIC1, Suppressor of kinetochore protein 1 | | Authors: | Tang, X, Orlicky, S, Mittag, T, Csizmok, V, Pawson, T, Forman-Kay, J, Sicheri, F, Tyers, M. | | Deposit date: | 2011-12-20 | | Release date: | 2012-05-02 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.306 Å) | | Cite: | Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase.
Proc.Natl.Acad.Sci.USA, 109, 2012
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9CB3
 | | E2F1-Cyclin F Interface | | Descriptor: | Cyclin-F, E2F1 peptide, S-phase kinase-associated protein 1 | | Authors: | Ngoi, P, Serrao, V.H, Rubin, S.M. | | Deposit date: | 2024-06-18 | | Release date: | 2025-02-12 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural mechanism for recognition of E2F1 by the ubiquitin ligase adaptor Cyclin F.
Biorxiv, 2025
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6BYH
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4UI9
 | | Atomic structure of the human Anaphase-Promoting Complex | | Descriptor: | ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ... | | Authors: | Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D. | | Deposit date: | 2015-03-27 | | Release date: | 2015-06-17 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
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