6O60

Crystal structure of GGTase3-FBXL2-SKP1 complex

Summary for 6O60

Entry DOI	10.2210/pdb6o60/pdb
Descriptor	Protein prenyltransferase alpha subunit repeat-containing protein 1, Geranylgeranyl transferase type-2 subunit beta, F-box/LRR-repeat protein 2, ... (6 entities in total)
Functional Keywords	f-box, leucine-rich repeat, ggtase subunits, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	149901.83
Authors	Wang, H.,Zheng, N. (deposition date: 2019-03-04, release date: 2019-06-26, Last modification date: 2023-10-11)
Primary citation	Kuchay, S.,Wang, H.,Marzio, A.,Jain, K.,Homer, H.,Fehrenbacher, N.,Philips, M.R.,Zheng, N.,Pagano, M. GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase. Nat.Struct.Mol.Biol., 26:628-636, 2019 Cited by PubMed: 31209342 DOI: 10.1038/s41594-019-0249-3 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.503 Å)

Structure validation