5LSD
 
 | | recombinant mouse Nerve Growth Factor | | Descriptor: | Beta-nerve growth factor | | Authors: | Paoletti, F, de Chiara, C, Kelly, G, Lamba, D, Cattaneo, A, Pastore, A. | | Deposit date: | 2016-08-25 | | Release date: | 2017-07-05 | | Last modified: | 2024-11-13 | | Method: | SOLUTION NMR | | Cite: | Conformational Rigidity within Plasticity Promotes Differential Target Recognition of Nerve Growth Factor.
Front Mol Biosci, 3, 2016
|
|
6YW8
 | |
1WWW
 | |
6XUO
 | | mature recombinant horse NGF | | Descriptor: | Nerve growth factor, ZINC ION | | Authors: | Kalnins, G. | | Deposit date: | 2020-01-20 | | Release date: | 2020-01-29 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.803 Å) | | Cite: | Mature horse nerve growth factor at 2.8 angstrom resolution
To Be Published
|
|
9FIK
 | | Structure of the FAB fragment of the Antibody NTF30037 in complex with NTF3 | | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NTF30037 Heavy Chain, ... | | Authors: | Gallego, P, Aagaard, A, Sjogren, T, Chin, S, Neal, F. | | Deposit date: | 2024-05-29 | | Release date: | 2025-04-02 | | Last modified: | 2025-04-09 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Identification of unique binding mode anti-NTF3 antibodies from a novel long VH CDR3 phage display library.
Slas Discov, 31, 2025
|
|
5JZ7
 | | NGF IN COMPLEX WITH MEDI578 scFv | | Descriptor: | Beta-nerve growth factor, MEDI578 scFv, heavy chain, ... | | Authors: | Olsson, L.-L, Aagaard, A. | | Deposit date: | 2016-05-16 | | Release date: | 2017-01-11 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
|
|
1NT3
 | | HUMAN NEUROTROPHIN-3 | | Descriptor: | PROTEIN (NEUROTROPHIN-3) | | Authors: | Butte, M.J, Hwang, P.K, Mobley, W.C, Fletterick, R.J. | | Deposit date: | 1999-05-17 | | Release date: | 1999-06-06 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors.
Biochemistry, 37, 1998
|
|
4XPJ
 | | Crystal structure of Nerve growth factor in complex with lysophosphatidylinositol | | Descriptor: | (2R)-2-hydroxy-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6R)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl tridecanoate, Beta-nerve growth factor | | Authors: | Sun, H.L, Jiang, T. | | Deposit date: | 2015-01-17 | | Release date: | 2015-07-15 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.605 Å) | | Cite: | The structure of nerve growth factor in complex with lysophosphatidylinositol
Acta Crystallogr.,Sect.F, 71, 2015
|
|
4ZBN
 | |
4EC7
 | | Cobra NGF in complex with lipid | | Descriptor: | (2S)-1-hydroxy-3-(tetradecanoyloxy)propan-2-yl docosanoate, Venom nerve growth factor | | Authors: | Jiang, T, Wang, F, Tong, Q. | | Deposit date: | 2012-03-26 | | Release date: | 2012-09-12 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
|
|
4EDW
 | |
4EFV
 | | Crystal structure of OIF from Llama seminal plasma | | Descriptor: | CHLORIDE ION, Ovulation-inducing factor (OIF), PHOSPHATE ION | | Authors: | Van Straaten, K.E, Leduc, Y.A, Ratto, M.H, Valderrama, X.P, Delbaere, T.J, Pierson, R.A, Adams, G.P. | | Deposit date: | 2012-03-30 | | Release date: | 2012-08-22 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | The nerve of ovulation-inducing factor in semen.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4EDX
 | | Nerve Growth Factor in Complex with Fab from mouse mAb 911 | | Descriptor: | Beta-nerve growth factor, heavy chain of Fab of murine anti-NGF, light chain of FAB of murine anti-NGF | | Authors: | Eigenbrot, C, Ultsch, M. | | Deposit date: | 2012-03-27 | | Release date: | 2014-04-02 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs, 6
|
|
4EAX
 | | Mouse NGF in complex with Lyso-PS | | Descriptor: | Beta-nerve growth factor, O-[(S)-hydroxy{[(2S)-2-hydroxy-3-(octadec-9-enoyloxy)propyl]oxy}phosphoryl]-L-serine | | Authors: | Jiang, T, Tong, Q. | | Deposit date: | 2012-03-23 | | Release date: | 2012-09-12 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and functional insights into lipid-bound nerve growth factors
Faseb J., 26, 2012
|
|
1B98
 | | NEUROTROPHIN 4 (HOMODIMER) | | Descriptor: | CHLORIDE ION, PROTEIN (NEUROTROPHIN-4) | | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | | Deposit date: | 1999-02-22 | | Release date: | 1999-02-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
|
|
1BET
 | | NEW PROTEIN FOLD REVEALED BY A 2.3 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF NERVE GROWTH FACTOR | | Descriptor: | BETA-NERVE GROWTH FACTOR | | Authors: | Mcdonald, N.Q, Lapatto, R, Murray-Rust, J, Gunning, J, Wlodawer, A, Blundell, T.L. | | Deposit date: | 1993-04-08 | | Release date: | 1994-05-31 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor.
Nature, 354, 1991
|
|
1BTG
 | |
1B8K
 | | Neurotrophin-3 from Human | | Descriptor: | PROTEIN (NEUROTROPHIN-3) | | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | | Deposit date: | 1999-02-01 | | Release date: | 1999-02-09 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
|
|
1B8M
 | | BRAIN DERIVED NEUROTROPHIC FACTOR, NEUROTROPHIN-4 | | Descriptor: | PROTEIN (BRAIN DERIVED NEUROTROPHIC FACTOR), PROTEIN (NEUROTROPHIN-4) | | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y, Choe, S. | | Deposit date: | 1999-02-01 | | Release date: | 1999-02-09 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The structures of the neurotrophin 4 homodimer and the brain-derived neurotrophic factor/neurotrophin 4 heterodimer reveal a common Trk-binding site.
Protein Sci., 8, 1999
|
|
1BND
 | | STRUCTURE OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR(SLASH)NEUROTROPHIN 3 HETERODIMER | | Descriptor: | BRAIN DERIVED NEUROTROPHIC FACTOR, ISOPROPYL ALCOHOL, NEUROTROPHIN 3 | | Authors: | Robinson, R.C, Radziejewski, C, Stuart, D.I, Jones, E.Y. | | Deposit date: | 1994-12-12 | | Release date: | 1996-04-04 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the brain-derived neurotrophic factor/neurotrophin 3 heterodimer.
Biochemistry, 34, 1995
|
|
1HCF
 | | Crystal structure of TrkB-d5 bound to neurotrophin-4/5 | | Descriptor: | BDNF/NT-3 GROWTH FACTORS RECEPTOR, NEUROTROPHIN-4, SULFATE ION | | Authors: | Banfield, M.J, Naylor, R.L, Robertson, A.G.S, Allen, S.J, Dawbarn, D, Brady, R.L. | | Deposit date: | 2001-05-03 | | Release date: | 2001-12-06 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Specificity in Trk-Receptor:Neurotrophin Interaction: The Crystal Structure of Trkb-D5 in Complex with Neurotrophin-4/5
Structure, 9, 2001
|
|
6FFY
 | | Structure of the mouse SorCS2-NGF complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-nerve growth factor, VPS10 domain-containing receptor SorCS2, ... | | Authors: | Leloup, N.O.L, Janssen, B.J.C. | | Deposit date: | 2018-01-09 | | Release date: | 2018-08-01 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (3.9 Å) | | Cite: | Structural insights into SorCS2-Nerve Growth Factor complex formation.
Nat Commun, 9, 2018
|
|
2IFG
 | |
3BUK
 | | Crystal Structure of the Neurotrophin-3 and p75NTR Symmetrical Complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neurotrophin-3, Tumor necrosis factor receptor superfamily member 16 | | Authors: | Jiang, T, Gong, Y, Cao, P, Yu, H.J. | | Deposit date: | 2008-01-02 | | Release date: | 2008-07-15 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of the neurotrophin-3 and p75NTR symmetrical complex.
Nature, 454, 2008
|
|
3IJ2
 | | Ligand-receptor structure | | Descriptor: | Beta-nerve growth factor, Nerve growth factor receptor (TNFR superfamily, member 16) | | Authors: | Feng, D, Garcia, K.C. | | Deposit date: | 2009-08-03 | | Release date: | 2010-01-12 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (3.75 Å) | | Cite: | Molecular and structural insight into proNGF engagement of p75NTR and sortilin.
J.Mol.Biol., 396, 2010
|
|
