1NT3

HUMAN NEUROTROPHIN-3

Summary for 1NT3

DescriptorPROTEIN (NEUROTROPHIN-3) (2 entities in total)
Functional Keywordsneurotrophin, growth factor, cystine knot, hormone-growth factor-neuropeptide complex, hormone/growth factor/neuropeptide
Biological sourceHomo sapiens (human)
Cellular locationSecreted P20783
Total number of polymer chains1
Total molecular weight13649.4
Authors
Butte, M.J.,Hwang, P.K.,Mobley, W.C.,Fletterick, R.J. (deposition date: 1999-05-17, release date: 1999-06-06, Last modification date: 2011-11-16)
Primary citation
Butte, M.J.,Hwang, P.K.,Mobley, W.C.,Fletterick, R.J.
Crystal structure of neurotrophin-3 homodimer shows distinct regions are used to bind its receptors.
Biochemistry, 37:16846-16852, 1998
PubMed: 9836577 (PDB entries with the same primary citation)
DOI: 10.1021/bi981254o
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers28 7.5% 11.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171916
PDB entries from 2020-12-02