4ZBN
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Summary for 4ZBN
Entry DOI | 10.2210/pdb4zbn/pdb |
Descriptor | DNA (28-MER), Beta-nerve growth factor, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
Functional Keywords | complex, aptamer, immune system-dna complex, immune system/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted: P01138 |
Total number of polymer chains | 4 |
Total formula weight | 46860.50 |
Authors | Davies, D.R.,Edwards, T.E. (deposition date: 2015-04-15, release date: 2015-06-10, Last modification date: 2015-07-15) |
Primary citation | Jarvis, T.C.,Davies, D.R.,Hisaminato, A.,Resnicow, D.I.,Gupta, S.,Waugh, S.M.,Nagabukuro, A.,Wadatsu, T.,Hishigaki, H.,Gawande, B.,Zhang, C.,Wolk, S.K.,Mayfield, W.S.,Nakaishi, Y.,Burgin, A.B.,Stewart, L.J.,Edwards, T.E.,Gelinas, A.D.,Schneider, D.J.,Janjic, N. Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor. Structure, 23:1293-1304, 2015 Cited by PubMed: 26027732DOI: 10.1016/j.str.2015.03.027 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.447 Å) |
Structure validation
Download full validation report