4ZBN
Non-helical DNA Triplex Forms a Unique Aptamer Scaffold for High Affinity Recognition of Nerve Growth Factor
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (D, E) | DNA (28-MER) | polymer | 28 | 9795.7 | 2 | synthetic construct | ||
2 | C, D (A, B) | Beta-nerve growth factor | polymer | 120 | 13515.4 | 2 | UniProt (P01138) Pfam (PF00243) | Homo sapiens (Human) | Beta-NGF |
3 | E (D) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | F, G, H, I (D, E, A, B) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 46622.2 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 238.3 | |
All* | Total formula weight | 46860.5 |