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2IFG

Structure of the extracellular segment of human TRKA in complex with nerve growth factor

Summary for 2IFG
Entry DOI10.2210/pdb2ifg/pdb
DescriptorHigh affinity nerve growth factor receptor, Beta-nerve growth factor, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywordstrk, trka, ngf, nerve growth factor, receptor-ligand complex, transferase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight109542.64
Authors
He, X.,Garcia, K.C. (deposition date: 2006-09-20, release date: 2007-02-13, Last modification date: 2023-08-30)
Primary citationWehrman, T.,He, X.,Raab, B.,Dukipatti, A.,Blau, H.,Garcia, K.C.
Structural and mechanistic insights into nerve growth factor interactions with the TrkA and p75 receptors.
Neuron, 53:25-38, 2007
Cited by
PubMed: 17196528
DOI: 10.1016/j.neuron.2006.09.034
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.4 Å)
Structure validation

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