6FFY

Structure of the mouse SorCS2-NGF complex

Summary for 6FFY

• Entry DOI: 10.2210/pdb6ffy/pdb
• Related: 6FG9
• Descriptor: VPS10 domain-containing receptor SorCS2, Beta-nerve growth factor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: sorcs2, prongf, p75ntr, apoptosis, vps10, sortilin, neuroplasticity
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 139087.74

Authors

Leloup, N.O.L.,Janssen, B.J.C. (deposition date: 2018-01-09, release date: 2018-08-01, Last modification date: 2024-01-17)

• Primary citation: Leloup, N.,Chataigner, L.M.P.,Janssen, B.J.C.; Structural insights into SorCS2-Nerve Growth Factor complex formation.; Nat Commun, 9:2979-2979, 2018; PubMed: 30061605; DOI: 10.1038/s41467-018-05405-z

Experimental method

X-RAY DIFFRACTION (3.9 Å)