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PDB: 24 results

3CNK
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BU of 3cnk by Molmil
Crystal Structure of the dimerization domain of human filamin A
Descriptor: Filamin-A, SULFATE ION
Authors:Lee, B.J, Seo, M.D, Seok, S.H, Lee, S.J, Kwon, A.R, Im, H.
Deposit date:2008-03-26
Release date:2009-02-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Crystal structure of the dimerization domain of human filamin A
Proteins, 75, 2008
4M9P
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BU of 4m9p by Molmil
Crystal structure of the human filamin A Ig-like domains 3-5
Descriptor: Filamin-A
Authors:Seppala, J, Pentikainen, U, Ylanne, J.
Deposit date:2013-08-15
Release date:2014-02-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A Novel Structural Unit in the N-terminal Region of Filamins.
J.Biol.Chem., 289, 2014
7SC4
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BU of 7sc4 by Molmil
filamin complex-1
Descriptor: Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION
Authors:Liu, J, Qin, J.
Deposit date:2021-09-27
Release date:2023-04-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
2W0P
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BU of 2w0p by Molmil
Crystal structure of the filamin A repeat 21 complexed with the migfilin peptide
Descriptor: FILAMIN-A, FILAMIN-BINDING LIM PROTEIN 1, SULFATE ION
Authors:Ruskamo, S, Ylanne, J.
Deposit date:2008-08-20
Release date:2008-09-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis of the Migfilin-Filamin Interaction and Competition with Integrin {Beta} Tails.
J.Biol.Chem., 283, 2008
4P3W
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BU of 4p3w by Molmil
Crystal structure of the human filamin A Ig-like domains 20-21 in complex with migfilin peptide
Descriptor: Filamin-A, Filamin-binding LIM protein 1, PRASEODYMIUM ION, ...
Authors:Seppala, J, Pentikainen, U, Ylanne, J.
Deposit date:2014-03-10
Release date:2015-08-12
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the human filamin A Ig-like domains 20-21 in complex with migfilin peptide
To Be Published
2BRQ
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BU of 2brq by Molmil
Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide
Descriptor: FILAMIN A, GLUTATHIONE, GLYCEROL, ...
Authors:Kiema, T.-R, Ylanne, J.
Deposit date:2005-05-11
Release date:2006-02-07
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Molecular Basis of Filamin Binding to Integrins and Competition with Talin.
Mol.Cell, 21, 2006
2JF1
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CRYSTAL STRUCTURE OF THE FILAMIN A REPEAT 21 COMPLEXED WITH THE INTEGRIN BETA2 CYTOPLASMIC TAIL PEPTIDE
Descriptor: FILAMIN-A, GLYCEROL, INTEGRIN BETA-2 SUBUNIT
Authors:Kiema, T, Ylanne, J.
Deposit date:2007-01-25
Release date:2008-02-05
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Beta2 Integrin Phosphorylation on Thr758 Acts as a Molecular Switch to Regulate 14-3-3 and Filamin Binding.
Blood, 112, 2008
3HOP
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BU of 3hop by Molmil
Structure of the actin-binding domain of human filamin A
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-03
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
3HOC
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Structure of the actin-binding domain of human filamin A mutant E254K
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-02
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
6EW1
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BU of 6ew1 by Molmil
Crystal structure of the Filamin A Ig-like domains 3-5 mutant P637Q
Descriptor: Filamin-A
Authors:Haataja, T.J.K, Pentikainen, U.
Deposit date:2017-11-03
Release date:2018-10-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.30700827 Å)
Cite:Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A.
Structure, 27, 2019
2BP3
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BU of 2bp3 by Molmil
Crystal structure of Filamin A domain 17 and GPIb alpha cytoplasmic domain complex
Descriptor: FILAMIN A, GLYCEROL, PLATELET GLYCOPROTEIN IB ALPHA CHAIN
Authors:Pudas, R, Ylanne, J.
Deposit date:2005-04-18
Release date:2005-11-30
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The Structure of the Gpib-Filamin a Complex.
Blood, 107, 2006
3RGH
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BU of 3rgh by Molmil
Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens
Descriptor: ACETATE ION, Filamin-A
Authors:Page, R.C, Clark, J, Misra, S.
Deposit date:2011-04-08
Release date:2011-08-03
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.44 Å)
Cite:Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens.
Acta Crystallogr.,Sect.F, 67, 2011
2J3S
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BU of 2j3s by Molmil
Crystal structure of the human filamin A Ig domains 19 to 21
Descriptor: 1,4-DIETHYLENE DIOXIDE, BROMIDE ION, FILAMIN-A, ...
Authors:Kiema, T.-R, Ylanne, J.
Deposit date:2006-08-23
Release date:2007-10-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Three Tandem Filamin Domains Reveals Auto-Inhibition of Ligand-Binding.
Embo J., 26, 2007
3HOR
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BU of 3hor by Molmil
Structure of the actin-binding domain of human filamin A (reduced)
Descriptor: Filamin-A, PHOSPHATE ION
Authors:Clark, A.R, Sawyer, G.M, Robertson, S.P, Sutherland-Smith, A.J.
Deposit date:2009-06-03
Release date:2009-10-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders
Hum.Mol.Genet., 18, 2009
3ISW
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BU of 3isw by Molmil
Crystal structure of filamin-A immunoglobulin-like repeat 21 bound to an N-terminal peptide of CFTR
Descriptor: Cystic fibrosis transmembrane conductance regulator, Filamin-A
Authors:Xu, Z, Page, R, Qin, J, Ithychanda, S.S, Liu, J.M, Misra, S.
Deposit date:2009-08-27
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin.
J.Biol.Chem., 285, 2010
2WFN
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BU of 2wfn by Molmil
Filamin A actin binding domain
Descriptor: FILAMIN-A, SULFATE ION
Authors:Ruskamo, S, Ylanne, J.
Deposit date:2009-04-09
Release date:2009-10-27
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of the Human Filamin a Actin-Binding Domain
Acta Crystallogr.,Sect.D, 65, 2009
6D8C
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BU of 6d8c by Molmil
Cryo-EM structure of FLNaABD E254K bound to phalloidin-stabilized F-actin
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Iwamoto, D.V, Huehn, A.R, Simon, B, Huet-Calderwood, C, Baldassarre, M, Sindelar, C.V, Calderwood, D.A.
Deposit date:2018-04-26
Release date:2018-09-19
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of the filamin A actin-binding domain interaction with F-actin.
Nat. Struct. Mol. Biol., 25, 2018
5XR1
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BU of 5xr1 by Molmil
Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
Descriptor: C-terminal peptide of Integrin beta-2,Filamin-A IG21 domain
Authors:Chatterjee, D, Lu, L.Z, Bhattacharjya, S.
Deposit date:2017-06-07
Release date:2018-06-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure of FLN IG21 domain in complex with C-terminal peptide of beta-2
To Be Published
2AAV
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BU of 2aav by Molmil
Solution NMR structure of Filamin A domain 17
Descriptor: Filamin A
Authors:Nakamura, F, Pudas, R, Heikkinen, O, Permi, P, Kilpelainen, I, Munday, A.D, Hartwig, J.H, Stossel, T.P, Ylanne, J.
Deposit date:2005-07-14
Release date:2006-05-02
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The structure of the GPIb-filamin A complex
Blood, 107, 2006
2K3T
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BU of 2k3t by Molmil
Solution Structure of IG-Like Domain 23 from Human Filamin A
Descriptor: Filamin-A
Authors:Heikkinen, O.K, Ylanne, J, Kilpelainen, I, Kupiainen, O.
Deposit date:2008-05-16
Release date:2009-03-31
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Molecular basis of filamin A-FilGAP interaction and its impairment in congenital disorders associated with filamin A mutations
Plos One, 4, 2009
7SFT
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BU of 7sft by Molmil
Filamin complex-2
Descriptor: Filamin-A, Integrin alpha-IIb light chain, form 2
Authors:Liu, J, Qin, J.
Deposit date:2021-10-04
Release date:2023-04-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.
Blood, 141, 2023
2K7P
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BU of 2k7p by Molmil
Filamin A Ig-like domains 16-17
Descriptor: Filamin-A
Authors:Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J.
Deposit date:2008-08-19
Release date:2009-07-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
2K7Q
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BU of 2k7q by Molmil
Filamin A Ig-like domains 18-19
Descriptor: Filamin-A
Authors:Heikkinen, O.K, Kilpelainen, I, Koskela, H, Permi, P, Heikkinen, S, Ylanne, J.
Deposit date:2008-08-19
Release date:2009-07-07
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Atomic structures of two novel immunoglobulin-like domain pairs in the actin cross-linking protein filamin
J.Biol.Chem., 284, 2009
2MTP
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BU of 2mtp by Molmil
The structure of Filamin repeat 21 bound to integrin
Descriptor: Filamin-A, Integrin alpha-IIb, Integrin beta-3
Authors:Liu, J, Qin, J.
Deposit date:2014-08-28
Release date:2015-04-01
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural mechanism of integrin inactivation by filamin.
Nat.Struct.Mol.Biol., 22, 2015

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