2W0P
Crystal structure of the filamin A repeat 21 complexed with the migfilin peptide
Summary for 2W0P
Entry DOI | 10.2210/pdb2w0p/pdb |
Related | 2AAV 2BP3 2BRQ 2J3S 2JF1 |
Descriptor | FILAMIN-A, FILAMIN-BINDING LIM PROTEIN 1, SULFATE ION, ... (4 entities in total) |
Functional Keywords | alternative splicing, cytoskeleton-complex, phosphoprotein, disease mutation, immunoglobulin like, zinc, filamin, complex, integrin, migfilin, receptor, polymorphism, cytoskeleton, actin-binding, cell junction, cell adhesion, metal-binding, cytoplasm, lim domain, cell shape, acetylation |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm, cell cortex: P21333 Q8WUP2 |
Total number of polymer chains | 3 |
Total formula weight | 21220.36 |
Authors | Ruskamo, S.,Ylanne, J. (deposition date: 2008-08-20, release date: 2008-09-30, Last modification date: 2023-12-13) |
Primary citation | Lad, Y.,Jiang, P.,Ruskamo, S.,Harburger, D.S.,Ylanne, J.,Campbell, I.D.,Calderwood, D.A. Structural Basis of the Migfilin-Filamin Interaction and Competition with Integrin {Beta} Tails. J.Biol.Chem., 283:35154-, 2008 Cited by PubMed: 18829455DOI: 10.1074/JBC.M802592200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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