2BRQ
Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide
Summary for 2BRQ
Entry DOI | 10.2210/pdb2brq/pdb |
Related | 2BP3 |
Descriptor | FILAMIN A, INTEGRIN BETA-7 SUBUNIT, GLUTATHIONE, ... (5 entities in total) |
Functional Keywords | structural protein, cytoskeleton-complex, actin-binding, cytoskeleton, immunoglobulin like, integrin, cell adhesion |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm, cell cortex: P21333 Membrane; Single-pass type I membrane protein: P26010 |
Total number of polymer chains | 4 |
Total formula weight | 27834.66 |
Authors | Kiema, T.-R.,Ylanne, J. (deposition date: 2005-05-11, release date: 2006-02-07, Last modification date: 2023-12-13) |
Primary citation | Kiema, T.,Lad, Y.,Jiang, P.,Oxley, C.L.,Baldassarre, M.,Wegener, K.L.,Campbell, I.D.,Ylanne, J.,Calderwood, D.A. The Molecular Basis of Filamin Binding to Integrins and Competition with Talin. Mol.Cell, 21:337-, 2006 Cited by PubMed: 16455489DOI: 10.1016/J.MOLCEL.2006.01.011 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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