2BRQ

Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide

Summary for 2BRQ

• Entry DOI: 10.2210/pdb2brq/pdb
• Related: 2BP3
• Descriptor: FILAMIN A, INTEGRIN BETA-7 SUBUNIT, GLUTATHIONE, ... (5 entities in total)
• Functional Keywords: structural protein, cytoskeleton-complex, actin-binding, cytoskeleton, immunoglobulin like, integrin, cell adhesion
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm, cell cortex: P21333; Membrane; Single-pass type I membrane protein: P26010
• Total number of polymer chains: 4
• Total formula weight: 27834.66

Authors

Kiema, T.-R.,Ylanne, J. (deposition date: 2005-05-11, release date: 2006-02-07, Last modification date: 2023-12-13)

• Primary citation: Kiema, T.,Lad, Y.,Jiang, P.,Oxley, C.L.,Baldassarre, M.,Wegener, K.L.,Campbell, I.D.,Ylanne, J.,Calderwood, D.A.; The Molecular Basis of Filamin Binding to Integrins and Competition with Talin.; Mol.Cell, 21:337-, 2006; PubMed: 16455489; DOI: 10.1016/J.MOLCEL.2006.01.011

Experimental method

X-RAY DIFFRACTION (2.1 Å)