2BRQ
Crystal structure of the filamin A repeat 21 complexed with the integrin beta7 cytoplasmic tail peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FILAMIN A | polymer | 97 | 9965.0 | 2 | UniProt (P21333) Pfam (PF00630) | HOMO SAPIENS (HUMAN) | ALPHA-FILAMIN, FILAMIN 1, ENDOTHELIAL ACTIN- BINDING PROTEIN, ACTIN-BINDING PROTEIN 280, ABP-280, NONMUSCLE FILAMIN |
| 2 | C, D (C, D) | INTEGRIN BETA-7 SUBUNIT | polymer | 31 | 3552.9 | 2 | UniProt (P26010) Pfam (PF08725) | HOMO SAPIENS | |
| 3 | E, H (A, B) | GLUTATHIONE | non-polymer | 307.3 | 2 | Chemie (GSH) | |||
| 4 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A, B: 2236 - 2329 (UniProt: P21333)
| PDB | External Database | Details |
|---|---|---|
| Gly 2233 | - | expression tag |
| Ala 2234 | - | expression tag |
| Met 2235 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 27035.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 798.8 | |
| All* | Total formula weight | 27834.7 |
