7SC4

filamin complex-1

Summary for 7SC4

• Entry DOI: 10.2210/pdb7sc4/pdb
• Descriptor: Filamin-A/Integrin alpha-IIb light chain, form 2 chimera, SULFATE ION (3 entities in total)
• Functional Keywords: filamin, integrin, inside-out signaling, outside-in signaling, cell adhesion
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 26762.92

Authors

Liu, J.,Qin, J. (deposition date: 2021-09-27, release date: 2023-04-12, Last modification date: 2023-10-25)

• Primary citation: Liu, J.,Lu, F.,Ithychanda, S.S.,Apostol, M.,Das, M.,Deshpande, G.,Plow, E.F.,Qin, J.; A mechanism of platelet integrin alpha IIb beta 3 outside-in signaling through a novel integrin alpha IIb subunit-filamin-actin linkage.; Blood, 141:2629-2641, 2023; PubMed: 36867840; DOI: 10.1182/blood.2022018333

Experimental method

X-RAY DIFFRACTION (1.85 Å)