3B34
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5MFR
| The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one | Descriptor: | Aminopeptidase N, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Peng, G, Olieric, V, McEwen, A.G, Schmitt, C, Albrecht, S, Cavarelli, J, Tarnus, C. | Deposit date: | 2016-11-18 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85, 2017
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3QJX
| Crystal Structure of E. coli Aminopeptidase N in complex with L-Serine | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | Authors: | Addlagatta, A, Gumpena, R, Kishor, C, Ganji, R.J. | Deposit date: | 2011-01-31 | Release date: | 2011-11-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases Chemmedchem, 6, 2011
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3B2X
| Crystal Structure of E. coli Aminopeptidase N in complex with Lysine | Descriptor: | Aminopeptidase N, GLYCEROL, LYSINE, ... | Authors: | Addlagatta, A, Gay, L, Matthews, B.W. | Deposit date: | 2007-10-19 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural basis for the unusual specificity of Escherichia coli aminopeptidase N. Biochemistry, 47, 2008
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2DQ6
| Crystal Structure of Aminopeptidase N from Escherichia coli | Descriptor: | Aminopeptidase N, SULFATE ION, ZINC ION | Authors: | Nakajima, Y, Onohara, Y, Ito, K, Yoshimoto, T. | Deposit date: | 2006-05-22 | Release date: | 2006-08-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli: Crystal structure and conformational change of the methionine 260 residue involved in substrate recognition J.Biol.Chem., 281, 2006
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2ZXG
| Aminopeptidase N complexed with the aminophosphinic inhibitor of PL250, a transition state analogue | Descriptor: | Aminopeptidase N, GLYCEROL, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ... | Authors: | Nakajima, Y, Ito, K, Yoshimoto, T. | Deposit date: | 2008-12-24 | Release date: | 2009-08-25 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250 Acta Crystallogr.,Sect.D, 65, 2009
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5YQB
| Crystal structure of E.coli aminopeptidase N in complex with Puromycin | Descriptor: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-06 | Release date: | 2018-11-14 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165, 2020
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5MFS
| The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one | Descriptor: | Aminopeptidase N, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Peng, G, Olieric, V, McEwen, A.G, Schmitt, C, Albrecht, S, Cavarelli, J, Tarnus, C. | Deposit date: | 2016-11-18 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85, 2017
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5YQ1
| Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine To Be Published
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5MFT
| The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-1-bromo-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one | Descriptor: | Aminopeptidase N, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Peng, G, Olieric, V, McEwen, A.G, Schmitt, C, Albrecht, S, Cavarelli, J, Tarnus, C. | Deposit date: | 2016-11-18 | Release date: | 2017-04-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.59 Å) | Cite: | Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85, 2017
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2DQM
| Crystal Structure of Aminopeptidase N complexed with bestatin | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Aminopeptidase N, SULFATE ION, ... | Authors: | Onohara, Y, Nakajima, Y, Ito, K, Yoshimoto, T. | Deposit date: | 2006-05-29 | Release date: | 2006-08-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli: Crystal structure and conformational change of the methionine 260 residue involved in substrate recognition J.Biol.Chem., 281, 2006
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5YQ2
| Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside | Descriptor: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | Authors: | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | Deposit date: | 2017-11-04 | Release date: | 2018-11-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside To Be Published
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2HPO
| Structure of Aminopeptidase N from E. coli Suggests a Compartmentalized, Gated Active Site | Descriptor: | Aminopeptidase N, GLYCEROL, ZINC ION | Authors: | Addlagatta, A, Matthews, B.W, Gay, L. | Deposit date: | 2006-07-17 | Release date: | 2006-08-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure of aminopeptidase N from Escherichia coli suggests a compartmentalized, gated active site. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3B37
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3B3B
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4XN8
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4Q4E
| Crystal structure of E.coli aminopeptidase N in complex with actinonin | Descriptor: | ACTINONIN, Aminopeptidase N, GLYCEROL, ... | Authors: | Reddi, R, Ganji, R.J, Addlagatta, A. | Deposit date: | 2014-04-14 | Release date: | 2015-04-15 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Sci., 24, 2015
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4XND
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4XNB
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4XO5
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4XN4
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4XMT
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4XO3
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3B2P
| Crystal structure of E. coli Aminopeptidase N in complex with arginine | Descriptor: | ARGININE, Aminopeptidase N, GLYCEROL, ... | Authors: | Anthony, A, Leslie, G, Matthews, B.W. | Deposit date: | 2007-10-18 | Release date: | 2008-05-06 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the unusual specificity of Escherichia coli aminopeptidase N. Biochemistry, 47, 2008
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4XN2
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