6Q0Q
 
 | | Crystal structure of Human galectin-3 CRD in complex with Methyl 3-O-(1-{3-O-[1-(b-D-galactopyranosyl)-1,2,3-triazol-4-yl]-methyl-b-D-galactopyranosyl}-1,2,3-triazol-4-yl)-methyl-b-D-galactopyranoside | | Descriptor: | (2~{R},3~{R},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-[4-[[(2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-methoxy-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]-3,5-bis(oxidanyl)oxan-4-yl]oxymethyl]-1,2,3-triazol-1-yl]oxane-3,4,5-triol, CHLORIDE ION, Galectin-3 | | Authors: | Kishor, C, Blanchard, H. | | Deposit date: | 2019-08-02 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.98601174 Å) | | Cite: | Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development.
Chem.Biol.Drug Des., 96, 2020
|
|
6Q17
 | | Crystal structure of Human galectin-3 CRD in complex with Methyl 3-O-[1-(b-D-galactopyranosyl)-1,2,3-triazol-4-yl]-methyl-b-D-galactopyranoside | | Descriptor: | CHLORIDE ION, Galectin-3, methyl 3-O-[(1-beta-D-galactopyranosyl-1H-1,2,3-triazol-4-yl)methyl]-beta-D-galactopyranoside | | Authors: | Kishor, C, Blanchard, H. | | Deposit date: | 2019-08-02 | | Release date: | 2020-04-29 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Linear triazole-linked pseudo oligogalactosides as scaffolds for galectin inhibitor development.
Chem.Biol.Drug Des., 96, 2020
|
|
3TB5
 | | Crystal Structure of the Enterococcus faecalis Methionine aminopeptidase apo form | | Descriptor: | CITRIC ACID, Methionine aminopeptidase | | Authors: | Kishor, C, Gumpena, R, Reddi, R, Addlagatta, A. | | Deposit date: | 2011-08-05 | | Release date: | 2012-08-08 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
MEDCHEMCOMM, 3, 2012
|
|
6B8K
 | |
6B94
 | |
4WXK
 | |
4WXL
 | |
7RDO
 | | Crystal structure of human galectin-3 CRD in complex with diselenodigalactoside | | Descriptor: | (2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]diselanyl}oxane-3,4,5-triol (non-preferred name), CHLORIDE ION, Galectin-3, ... | | Authors: | Kishor, C, Go, R.M, Blanchard, H. | | Deposit date: | 2021-07-10 | | Release date: | 2022-07-13 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Investigation of the Molecular Details of the Interactions of Selenoglycosides and Human Galectin-3.
Int J Mol Sci, 23, 2022
|
|
7RDP
 | |
4XQ6
 | |
6WAB
 | | Crystal structure of human galectin-4 C-terminal carbohydrate recognition domain in complex with galactose derivative | | Descriptor: | 2,6-anhydro-1,4-dideoxy-1-[4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl]-4-(4-phenyl-1H-1,2,3-triazol-1-yl)-D-glycero-L-manno-heptitol, GLYCEROL, Galectin-4 | | Authors: | Go, R.M, Kishor, C, Blanchard, H. | | Deposit date: | 2020-03-25 | | Release date: | 2021-04-07 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Crystal structure of human galectin-4 C-terminal carbohydrate recognition domain in complex with galactose derivative
To Be Published
|
|
6W4Z
 | | Galectin-8N terminal domain in complex with Methyl 3-O-[3-O-benzyloxy]-malonyl-beta-D-galactopyranoside | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Galectin-8, ... | | Authors: | Patel, B, Kishor, C, Blanchard, H. | | Deposit date: | 2020-03-12 | | Release date: | 2020-09-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.59 Å) | | Cite: | Rational Design and Synthesis of Methyl-beta-d-galactomalonyl Phenyl Esters as Potent Galectin-8 N Antagonists.
J.Med.Chem., 63, 2020
|
|
3QJX
 | | Crystal Structure of E. coli Aminopeptidase N in complex with L-Serine | | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | | Authors: | Addlagatta, A, Gumpena, R, Kishor, C, Ganji, R.J. | | Deposit date: | 2011-01-31 | | Release date: | 2011-11-16 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases
Chemmedchem, 6, 2011
|
|
3ROR
 | |
7RH0
 | |
7RGX
 | |
7RGY
 | |
7RGZ
 | |
7RH3
 | |
7RH1
 | |
7RH4
 | |
4XMX
 | |
4XN5
 | |
4IEC
 | | Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c | | Descriptor: | COBALT (II) ION, Methionine aminopeptidase 2, POTASSIUM ION | | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | | Deposit date: | 2012-12-13 | | Release date: | 2013-12-18 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
|
|
4IF7
 | | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide | | Descriptor: | (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2 | | Authors: | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | | Deposit date: | 2012-12-14 | | Release date: | 2013-12-18 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
|
|
