4IEC
Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c
Summary for 4IEC
| Entry DOI | 10.2210/pdb4iec/pdb |
| Related | 4IDY 4IF7 |
| Descriptor | Methionine aminopeptidase 2, COBALT (II) ION, POTASSIUM ION, ... (4 entities in total) |
| Functional Keywords | 2-hydroxyethyl disulfide, pita-bread fold, methionine aminopeptidase, cobalt, hydrolase |
| Biological source | Mycobacterium tuberculosis |
| Total number of polymer chains | 1 |
| Total formula weight | 32059.98 |
| Authors | Reddi, R.,Gumpena, R.,Kishor, C.,Addlagatta, A. (deposition date: 2012-12-13, release date: 2013-12-18, Last modification date: 2019-11-20) |
| Primary citation | Reddi, R.,Arya, T.,Kishor, C.,Gumpena, R.,Ganji, R.J.,Bhukya, S.,Addlagatta, A. Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents Febs J., 281:4240-4248, 2014 Cited by PubMed: 24841365DOI: 10.1111/febs.12847 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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