2ZXG

Aminopeptidase N complexed with the aminophosphinic inhibitor of PL250, a transition state analogue

Summary for 2ZXG

Entry DOI	10.2210/pdb2zxg/pdb
Related	2DQ6 2DQM
Descriptor	Aminopeptidase N, ZINC ION, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ... (6 entities in total)
Functional Keywords	clan ma, family m1, zinc peptidase, inhibitor complex, transition state, aminopeptidase, cell inner membrane, cell membrane, hydrolase, membrane, metal-binding, metalloprotease, protease
Biological source	Escherichia coli K-12
Cellular location	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825
Total number of polymer chains	1
Total formula weight	100253.19
Authors	Nakajima, Y.,Ito, K.,Yoshimoto, T. (deposition date: 2008-12-24, release date: 2009-08-25, Last modification date: 2023-11-01)
Primary citation	Fournie-Zaluski, M.C.,Poras, H.,Roques, B.P.,Nakajima, Y.,Ito, K.,Yoshimoto, T. Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250 Acta Crystallogr.,Sect.D, 65:814-822, 2009 Cited by PubMed: 19622865 DOI: 10.1107/S090744490901779X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation