5MFS

The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-4-phenyl-5,7,8,9-tetrahydrobenzocyclohepten-6-one

Summary for 5MFS

Entry DOI	10.2210/pdb5mfs/pdb
Descriptor	Aminopeptidase N, ZINC ION, [(7~{S})-6,6-bis(oxidanyl)-4-phenyl-5,7,8,9-tetrahydrobenzo[7]annulen-7-yl]azanium, ... (9 entities in total)
Functional Keywords	m1 aminopeptidase, hydrolase
Biological source	Escherichia coli
Cellular location	Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825
Total number of polymer chains	1
Total formula weight	104315.88
Authors	Peng, G.,Olieric, V.,McEwen, A.G.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C. (deposition date: 2016-11-18, release date: 2017-04-19, Last modification date: 2024-01-17)
Primary citation	Peng, G.,McEwen, A.G.,Olieric, V.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C. Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85:1413-1421, 2017 Cited by PubMed: 28383176 DOI: 10.1002/prot.25301 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.57 Å)

Structure validation