5YQB

Crystal structure of E.coli aminopeptidase N in complex with Puromycin

Summary for 5YQB

Entry DOI	10.2210/pdb5yqb/pdb
Descriptor	Aminopeptidase N, ZINC ION, O-methyl-L-tyrosine, ... (6 entities in total)
Functional Keywords	puromycin, m1 class aminopeptidase, hydrolase
Biological source	Escherichia coli (strain K12)
Total number of polymer chains	1
Total formula weight	101978.24
Authors	Marapaka, A.K.,Ganji, R.J.,Reddi, R.,Addlagatta, A. (deposition date: 2017-11-06, release date: 2018-11-14, Last modification date: 2023-11-22)
Primary citation	Reddi, R.,Ganji, R.J.,Marapaka, A.K.,Bala, S.C.,Yerra, N.V.,Haque, N.,Addlagatta, A. Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis Int.J.Biol.Macromol., 165:1373-1381, 2020 Cited by DOI: 10.1016/j.ijbiomac.2020.10.035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation