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PDB: 14 results

4HDO
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BU of 4hdo by Molmil
Crystal structure of the binary Complex of KRIT1 bound to the Rap1 GTPase
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
4JIF
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BU of 4jif by Molmil
Co-crystal structure of ICAP1 PTB domain in complex with a KRIT1 peptide
Descriptor: Integrin beta-1-binding protein 1, Krev interaction trapped protein 1
Authors:Liu, W, Boggon, T.J.
Deposit date:2013-03-05
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Cocrystal structure of the ICAP1 PTB domain in complex with a KRIT1 peptide.
Acta Crystallogr.,Sect.F, 69, 2013
6OQ4
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BU of 6oq4 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi1
Descriptor: 2-{(Z)-[(2-hydroxynaphthalen-1-yl)methylidene]amino}-N-[(1S)-1-phenylethyl]benzamide, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-04-25
Release date:2020-06-24
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021
6OQ3
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BU of 6oq3 by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi2
Descriptor: 2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-04-25
Release date:2020-06-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells
Faseb Bioadv, 2021
6UZK
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BU of 6uzk by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and HKi6
Descriptor: 2-hydroxy-6-methoxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2019-11-15
Release date:2020-11-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.924 Å)
Cite:Inhibition of the HEG1-KRIT1 interaction increases KLF4 and KLF2 expression in endothelial cells.
Faseb Bioadv, 3, 2021
4DXA
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BU of 4dxa by Molmil
Co-crystal structure of Rap1 in complex with KRIT1
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Li, X, Zhang, R, Boggon, T.J.
Deposit date:2012-02-27
Release date:2012-05-16
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
J.Biol.Chem., 287, 2012
4HDQ
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BU of 4hdq by Molmil
Crystal Structure of the Ternary Complex of KRIT1 bound to both the Rap1 GTPase and the Heart of Glass (HEG1) cytoplasmic tail
Descriptor: GLYCEROL, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Gingras, A.R.
Deposit date:2012-10-02
Release date:2013-07-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail.
J.Biol.Chem., 288, 2013
8SU8
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BU of 8su8 by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde).
Descriptor: (6P)-6-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-05-11
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T09
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BU of 8t09 by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-ethynyl-2-hydroxy-1-naphthaldehyde)
Descriptor: 6-ethynyl-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-05-31
Release date:2023-12-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
8T7V
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BU of 8t7v by Molmil
Co-crystal structure of KRIT1 with a 1-hydroxy 2-naphthaldehyde derivative (6-(furan-2-yl)-2-hydroxy-1-naphthaldehyde)
Descriptor: (7M)-7-(furan-2-yl)-2-hydroxynaphthalene-1-carbaldehyde, Krev interaction trapped protein 1, MAGNESIUM ION, ...
Authors:Bruystens, J.G.H.
Deposit date:2023-06-21
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Acs Pharmacol Transl Sci, 6, 2023
3U7D
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BU of 3u7d by Molmil
Crystal structure of the KRIT1/CCM1 FERM domain in complex with the heart of glass (HEG1) cytoplasmic tail
Descriptor: Krev interaction trapped protein 1, Protein HEG homolog 1
Authors:Gingras, A.R, Liu, J.J, Ginsberg, M.H, Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2011-10-13
Release date:2012-09-12
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of the junctional anchorage of the cerebral cavernous malformations complex.
J.Cell Biol., 199, 2012
4DX8
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BU of 4dx8 by Molmil
ICAP1 in complex with KRIT1 N-terminus
Descriptor: BROMIDE ION, Integrin beta-1-binding protein 1, Krev interaction trapped protein 1
Authors:Liu, W, Draheim, K, Zhang, R, Calderwood, D.A, Boggon, T.J.
Deposit date:2012-02-27
Release date:2013-01-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Mechanism for KRIT1 Release of ICAP1-Mediated Suppression of Integrin Activation.
Mol.Cell, 49, 2013
5D68
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BU of 5d68 by Molmil
Crystal structure of KRIT1 ARD-FERM
Descriptor: Krev interaction trapped protein 1
Authors:Zhang, R, Li, X, Boggon, T.J.
Deposit date:2015-08-11
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.908 Å)
Cite:Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
4TKN
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BU of 4tkn by Molmil
Structure of the SNX17 FERM domain bound to the second NPxF motif of KRIT1
Descriptor: Krev interaction trapped protein 1, Sorting nexin-17
Authors:Stiegler, A.L, Zhang, R, Liu, W, Boggon, T.J.
Deposit date:2014-05-27
Release date:2014-07-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Determinants for Binding of Sorting Nexin 17 (SNX17) to the Cytoplasmic Adaptor Protein Krev Interaction Trapped 1 (KRIT1).
J.Biol.Chem., 289, 2014

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PDB entries from 2024-08-28

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