7SEM
 
 | | Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | | Authors: | Rush, S.A, Hsieh, C.-L, McLellan, J.S. | | Deposit date: | 2021-09-30 | | Release date: | 2022-02-16 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins.
Nat Commun, 13, 2022
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8E15
 | | A computationally stabilized hMPV F protein | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, F1 protein with Fibritin peptide, F2 protein, ... | | Authors: | Huang, J, Gonzalez, K, Mousa, J, Strauch, E. | | Deposit date: | 2022-08-09 | | Release date: | 2023-04-12 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.41 Å) | | Cite: | A general computational design strategy for stabilizing viral class I fusion proteins.
Biorxiv, 2023
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7SEJ
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8TW3
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7TL0
 | | Cryo-EM structure of hMPV preF bound by Fabs MPE8 and SAN32-2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, ... | | Authors: | Rush, S.A, Hsieh, C.-L, McLellan, J.S. | | Deposit date: | 2022-01-17 | | Release date: | 2022-09-14 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.06 Å) | | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
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7TJQ
 | | SAN27-14 bound to a antigenic site V on prefusion-stabilized hMPV F | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0, MPE8 Fab heavy chain, ... | | Authors: | Hsieh, C.-L, McLellan, J.S, Rush, S.A. | | Deposit date: | 2022-01-16 | | Release date: | 2022-09-14 | | Last modified: | 2022-11-23 | | Method: | ELECTRON MICROSCOPY (3.13 Å) | | Cite: | Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus.
Cell Rep, 40, 2022
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5L1X
 | | Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Mas, V, Melero, J.A, McLellan, J.S. | | Deposit date: | 2016-07-29 | | Release date: | 2016-08-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Engineering, Structure and Immunogenicity of the Human Metapneumovirus F Protein in the Postfusion Conformation.
Plos Pathog., 12, 2016
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8EAY
 | | HMPV F complex with 4I3 Fab | | Descriptor: | 4I3 heavy chain protein, 4I3 light chain protein, Fusion glycoprotein F0 | | Authors: | Wen, X, Jardetzky, T.S. | | Deposit date: | 2022-08-30 | | Release date: | 2023-08-16 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.33 Å) | | Cite: | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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8EBP
 | | HMPV F dimer bound to RSV-199 Fab | | Descriptor: | Fusion glycoprotein F0, RSV-199 heavy chain protein, RSV-199 light chain protein | | Authors: | Wen, X, Jardetzky, T.S. | | Deposit date: | 2022-08-31 | | Release date: | 2023-08-16 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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8CW9
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8E2U
 | | HMPV F monomer bound to RSV-199 Fab | | Descriptor: | Fusion glycoprotein F0, RSV-199 heavy chain, RSV-199 light chain | | Authors: | Wen, X, Jardetzky, T.S. | | Deposit date: | 2022-08-16 | | Release date: | 2023-08-16 | | Last modified: | 2023-08-23 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode.
Cell Host Microbe, 31, 2023
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