8EAY

HMPV F complex with 4I3 Fab

Summary for 8EAY

Entry DOI	10.2210/pdb8eay/pdb
EMDB information	27808 27990
Descriptor	Fusion glycoprotein F0, 4I3 heavy chain protein, 4I3 light chain protein (3 entities in total)
Functional Keywords	human antibodies, rsv and mpv fusion protein, complex cryo-em structure, viral protein and antiviral protein, biosynthetic protein
Biological source	Human metapneumovirus A (human) More
Total number of polymer chains	3
Total formula weight	69859.11
Authors	Wen, X.,Jardetzky, T.S. (deposition date: 2022-08-30, release date: 2023-08-16, Last modification date: 2023-08-23)
Primary citation	Wen, X.,Suryadevara, N.,Kose, N.,Liu, J.,Zhan, X.,Handal, L.S.,Williamson, L.E.,Trivette, A.,Carnahan, R.H.,Jardetzky, T.S.,Crowe Jr., J.E. Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode. Cell Host Microbe, 31:1288-1300.e6, 2023 Cited by PubMed: 37516111 DOI: 10.1016/j.chom.2023.07.002 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.33 Å)

Structure validation