8FTO
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8G6W
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8G6Y
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8EMM
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8EIU
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![BU of 8eiu by Molmil](/molmil-images/mine/8eiu) | E. coli 70S ribosome with A-loop mutations U2554C and U2555C | Descriptor: | 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | Authors: | Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D. | Deposit date: | 2022-09-15 | Release date: | 2023-02-01 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.24 Å) | Cite: | Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome. Nucleic Acids Res., 51, 2023
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8G6X
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7S1K
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![BU of 7s1k by Molmil](/molmil-images/mine/7s1k) | Cfr-modified Escherichia coli stalled ribosome with antibiotic radezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Tsai, K, Stojkovic, V, Lee, D.J, Young, I.D, Szal, T, Vazquez-Laslop, N, Mankin, A.S, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7S1J
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![BU of 7s1j by Molmil](/molmil-images/mine/7s1j) | Wild-type Escherichia coli ribosome with antibiotic radezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (2.47 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7S1I
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![BU of 7s1i by Molmil](/molmil-images/mine/7s1i) | Wild-type Escherichia coli stalled ribosome with antibiotic radezolid | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D. | Deposit date: | 2021-09-02 | Release date: | 2022-03-02 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.48 Å) | Cite: | Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nat.Struct.Mol.Biol., 29, 2022
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7YLA
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![BU of 7yla by Molmil](/molmil-images/mine/7yla) | Cryo-EM structure of 50S-HflX complex | Descriptor: | 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | Authors: | Damu, W, Ning, G. | Deposit date: | 2022-07-25 | Release date: | 2023-01-04 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Cryo-EM Structure of the 50S-HflX Complex Reveals a Novel Mechanism of Antibiotic Resistance in E. coli Biorxiv, 2022
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7UG7
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![BU of 7ug7 by Molmil](/molmil-images/mine/7ug7) | 70S ribosome complex in an intermediate state of translocation bound to EF-G(GDP) stalled by Argyrin B | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | Authors: | Rundlet, E.J, Wieland, M, Holm, M, Koller, T.O, Blanchard, S.C, Wilson, D.N. | Deposit date: | 2022-03-24 | Release date: | 2022-05-18 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | The cyclic octapeptide antibiotic argyrin B inhibits translation by trapping EF-G on the ribosome during translocation. Proc.Natl.Acad.Sci.USA, 119, 2022
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8EKC
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8G7R
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8FZH
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![BU of 8fzh by Molmil](/molmil-images/mine/8fzh) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State II-D) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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8SYL
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![BU of 8syl by Molmil](/molmil-images/mine/8syl) | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2023-05-25 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8G7P
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8FZJ
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![BU of 8fzj by Molmil](/molmil-images/mine/8fzj) | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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8FZE
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![BU of 8fze by Molmil](/molmil-images/mine/8fze) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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6LKQ
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![BU of 6lkq by Molmil](/molmil-images/mine/6lkq) | The Structural Basis for Inhibition of Ribosomal Translocation by Viomycin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Zhang, L, Wang, Y.H, Lancaster, L, Zhou, J, Noller, H.F. | Deposit date: | 2019-12-20 | Release date: | 2020-05-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structural basis for inhibition of ribosomal translocation by viomycin. Proc.Natl.Acad.Sci.USA, 117, 2020
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8FZD
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![BU of 8fzd by Molmil](/molmil-images/mine/8fzd) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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8FZG
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![BU of 8fzg by Molmil](/molmil-images/mine/8fzg) | Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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8FZI
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![BU of 8fzi by Molmil](/molmil-images/mine/8fzi) | Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B) | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | Deposit date: | 2023-01-28 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The ribosome termination complex remodels release factor RF3 and ejects GDP Nat.Struct.Mol.Biol., 2024
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8G7Q
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8G7S
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8UQL
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![BU of 8uql by Molmil](/molmil-images/mine/8uql) | Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH in loaded state, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | Authors: | Molodtsov, V, Wang, C, Ebright, R.H. | Deposit date: | 2023-10-24 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome Nat.Struct.Mol.Biol., 2024
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