4XWX
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![BU of 4xwx by Molmil](/molmil-images/mine/4xwx) | Crystal structure of the PTB domain of SHC | Descriptor: | 1,2-ETHANEDIOL, SHC-transforming protein 1, SODIUM ION | Authors: | Chaikuad, A, Tallant, C, Krojer, T, Dixon-Clarke, S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2015-01-29 | Release date: | 2015-02-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Crystal structure of the PTB domain of SHC To Be Published
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6DM4
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![BU of 6dm4 by Molmil](/molmil-images/mine/6dm4) | Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila in complex with Homo sapiens Shc1 phospho-Tyr317 peptide | Descriptor: | RavO, SULFATE ION, Shc1 phospho-Tyr317 peptide | Authors: | Stogios, P.J, Evdokimova, E, Di Leo, R, Kaneko, T, Li, S, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2018-06-04 | Release date: | 2018-06-27 | Last modified: | 2020-01-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of the SH2 domain from RavO (Lpg1129) from Legionella pneumophila in complex with Homo sapiens Shc1 phospho-Tyr317 peptide To Be Published
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4JMH
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![BU of 4jmh by Molmil](/molmil-images/mine/4jmh) | |
5CZI
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![BU of 5czi by Molmil](/molmil-images/mine/5czi) | EGFR L858R MUTANT IN COMPLEX WITH A SHC PEPTIDE SUBSTRATE | Descriptor: | Epidermal growth factor receptor, SHC Peptide substrate | Authors: | Yun, C.H, Eck, M.J. | Deposit date: | 2015-07-31 | Release date: | 2015-09-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src. Nat.Struct.Mol.Biol., 22, 2015
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1MIL
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![BU of 1mil by Molmil](/molmil-images/mine/1mil) | TRANSFORMING PROTEIN | Descriptor: | SHC ADAPTOR PROTEIN | Authors: | Mikol, V. | Deposit date: | 1995-09-20 | Release date: | 1996-11-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the SH2 domain from the adaptor protein SHC: a model for peptide binding based on X-ray and NMR data. J.Mol.Biol., 254, 1995
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2L1C
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![BU of 2l1c by Molmil](/molmil-images/mine/2l1c) | |
1N3H
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![BU of 1n3h by Molmil](/molmil-images/mine/1n3h) | Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc | Descriptor: | SHC Transforming protein | Authors: | Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M. | Deposit date: | 2002-10-28 | Release date: | 2003-10-28 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc Structure, 11, 2003
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1QG1
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![BU of 1qg1 by Molmil](/molmil-images/mine/1qg1) | |
1SHC
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![BU of 1shc by Molmil](/molmil-images/mine/1shc) | SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | SHC, TRKA RECEPTOR PHOSPHOPEPTIDE | Authors: | Zhou, M.-M, Ravichandran, K.S, Olejniczak, E.T, Petros, A.M, Meadows, R.P, Sattler, M, Harlan, J.E, Wade, W.S, Burakoff, S.J, Fesik, S.W. | Deposit date: | 1996-03-27 | Release date: | 1997-05-15 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature, 378, 1995
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1OY2
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![BU of 1oy2 by Molmil](/molmil-images/mine/1oy2) | Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc | Descriptor: | SHC transforming protein | Authors: | Farooq, A, Zeng, L, Yan, K.S, Ravichandran, K.S, Zhou, M.-M. | Deposit date: | 2003-04-03 | Release date: | 2004-04-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Coupling of Folding and Binding in the PTB Domain of the Signaling Protein Shc Structure, 11, 2003
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1TCE
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![BU of 1tce by Molmil](/molmil-images/mine/1tce) | SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR, SHC | Authors: | Zhou, M.-M, Meadows, R.P, Logan, T.M, Yoon, H.S, Wade, W.R, Ravichandran, K.S, Burakoff, S.J, Feisk, S.W. | Deposit date: | 1996-03-27 | Release date: | 1997-05-15 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor. Proc.Natl.Acad.Sci.USA, 92, 1995
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