1TCE

SOLUTION NMR STRUCTURE OF THE SHC SH2 DOMAIN COMPLEXED WITH A TYROSINE-PHOSPHORYLATED PEPTIDE FROM THE T-CELL RECEPTOR, MINIMIZED AVERAGE STRUCTURE

Summary for 1TCE

DescriptorSHC, PHOSPHOPEPTIDE OF THE ZETA CHAIN OF T CELL RECEPTOR (2 entities in total)
Functional Keywordssh2 domain, complex (signal transduction-peptide), complex (signal transduction-peptide) complex, complex (signal transduction/peptide)
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm. Isoform p46Shc: Mitochondrion matrix. Isoform p66Shc: Mitochondrion (By similarity) P29353
Membrane; Single-pass type I membrane protein P20963
Total number of polymer chains2
Total molecular weight13653.22
Authors
Zhou, M.-M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.R.,Ravichandran, K.S.,Burakoff, S.J.,Feisk, S.W. (deposition date: 1996-03-27, release date: 1997-05-15, Last modification date: 2011-07-13)
Primary citation
Zhou, M.M.,Meadows, R.P.,Logan, T.M.,Yoon, H.S.,Wade, W.S.,Ravichandran, K.S.,Burakoff, S.J.,Fesik, S.W.
Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor.
Proc.Natl.Acad.Sci.USA, 92:7784-7788, 1995
PubMed: 7544002 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.92.17.7784
MImport into Mendeley
Experimental method
SOLUTION NMR
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Structure validation

ClashscoreRamachandran outliersSidechain outliers26 10.3% 31.7%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
171916
PDB entries from 2020-12-02