Shc-PTB:biphosphorylated integrin beta3 cytoplasmic tail complex (1:1)

Summary for 2L1C

DescriptorSHC (Src homology 2 domain containing) transforming protein 1, isoform CRA_d, Integrin beta-3 (2 entities in total)
Functional Keywordsshc-ptb, integrin beta3, cytoplasmic tail, cell adhesion
Biological sourceHomo sapiens (human)
Cellular locationMembrane; Single-pass type I membrane protein P05106
Total number of polymer chains2
Total molecular weight26451.86
Deshmukh, L.,Gorbatyuk, V.,Vinogradova, O. (deposition date: 2010-07-27, release date: 2010-08-18, Last modification date: 2012-04-18)
Primary citation
Deshmukh, L.,Gorbatyuk, V.,Vinogradova, O.
Integrin {beta}3 phosphorylation dictates its complex with the Shc phosphotyrosine-binding (PTB) domain.
J.Biol.Chem., 285:34875-34884, 2010
PubMed: 20739287 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.159087
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers17 3.0% 14.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation reportDownload
PDB entries from 2020-12-02