4XWX

Crystal structure of the PTB domain of SHC

Summary for 4XWX

DescriptorSHC-transforming protein 1, 1,2-ETHANEDIOL, SODIUM ION, ... (4 entities in total)
Functional Keywordssignaling protein, phosphotyrosine binding domain, signal transduction, structural genomics consortium (sgc)
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm. Isoform p46Shc: Mitochondrion matrix . Isoform p66Shc: Mitochondrion  P29353
Total number of polymer chains1
Total molecular weight18529.31
Authors
Primary citation
Chaikuad, A.,Tallant, C.,Krojer, T.,Dixon-Clarke, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC)
Crystal structure of the PTB domain of SHC
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.87 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.20510 0.8% 1.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
171588
PDB entries from 2020-11-25