1E1H
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2G7N
| Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, SILVER ION, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2007-03-13 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the Light Chain of Botulinum Neurotoxin Serotype A bound to Small Molecule Inhibitors To be Published
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6ES1
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2G7P
| Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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5MOY
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2G7Q
| Structure of the Light Chain of Botulinum Neurotoxin Serotype A Bound to Small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A, N-HYDROXY-L-ARGININAMIDE, ZINC ION | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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2G7K
| Structure of the Light Chain of Botulinum Neurotoxin, Serotype A Bound to small Molecule Inhibitors | Descriptor: | Botulinum neurotoxin type A | Authors: | Fu, Z, Baldwin, M.R, Boldt, G.E, Crawford, A, Janda, K.D, Barbieri, J.T, Kim, J.-J.P. | Deposit date: | 2006-02-28 | Release date: | 2006-08-15 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Light chain of botulinum neurotoxin serotype A: structural resolution of a catalytic intermediate. Biochemistry, 45, 2006
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8JLE
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8JLG
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLC
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JS8
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLH
| Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam | Descriptor: | (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JLF
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-02 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8JS9
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Botulinum neurotoxin, ... | Authors: | Yamagata, A. | Deposit date: | 2023-06-19 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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8K77
| Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and brivaracetam | Descriptor: | (2S)-2-[(4R)-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Yamagata, A. | Deposit date: | 2023-07-26 | Release date: | 2024-05-01 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Structural basis for antiepileptic drugs and botulinum neurotoxin recognition of SV2A. Nat Commun, 15, 2024
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