5MOY
Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
Summary for 5MOY
Entry DOI | 10.2210/pdb5moy/pdb |
Related | 4jra |
Descriptor | Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | beta-helix, vesicles, lumen, toxin, hydrolase, botox |
Biological source | Clostridium botulinum More |
Cellular location | Botulinum neurotoxin A light chain: Secreted. Botulinum neurotoxin A heavy chain: Secreted: Q45894 Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein : Q496J9 |
Total number of polymer chains | 2 |
Total formula weight | 66061.77 |
Authors | Benoit, R.M.,Scharer, M.A. (deposition date: 2016-12-14, release date: 2017-03-15, Last modification date: 2024-01-17) |
Primary citation | Benoit, R.M.,Scharer, M.A.,Wieser, M.M.,Li, X.,Frey, D.,Kammerer, R.A. Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C. Sci Rep, 7:43588-43588, 2017 Cited by PubMed: 28252640DOI: 10.1038/srep43588 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.302 Å) |
Structure validation
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