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PDB: 73 results

8FTO
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E. coli 70S ribosome with an improved MS2 tag inserted in H98
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Nissley, A.J, Cate, J.H.D.
Deposit date:2023-01-12
Release date:2023-08-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (1.85 Å)
Cite:Interactions between terminal ribosomal RNA helices stabilize the E. coli large ribosomal subunit.
Rna, 29, 2023
8G6W
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Structure of WT E.coli 70S ribosome complexed with mRNA, P-site fMet-NH-tRNAfMet and A-site ortho-aminobenzoic acid charged NH-tRNAPhe
Descriptor: 16S rRNA, 2-AMINO-BENZAMIDE, 23S rRNA, ...
Authors:Majumdar, C, Cate, J.H.D.
Deposit date:2023-02-16
Release date:2023-04-05
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.02 Å)
Cite:Aminobenzoic Acid Derivatives Obstruct Induced Fit in the Catalytic Center of the Ribosome.
Acs Cent.Sci., 9, 2023
8EMM
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Composite 70S ribosome structure for "Atomistic simulations of the E. coli ribosome provide selection criteria for translationally active substrates
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Watson, Z.L, Cate, J.H.D.
Deposit date:2022-09-28
Release date:2023-05-31
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.1 Å)
Cite:Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates.
Nat.Chem., 15, 2023
8EIU
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BU of 8eiu by Molmil
E. coli 70S ribosome with A-loop mutations U2554C and U2555C
Descriptor: 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
Authors:Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D.
Deposit date:2022-09-15
Release date:2023-02-01
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.24 Å)
Cite:Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome.
Nucleic Acids Res., 51, 2023
4TOI
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BU of 4toi by Molmil
Crystal structure of E.coli ribosomal protein S2 in complex with N-terminal domain of S1
Descriptor: 30S ribosomal protein S2,Ribosomal protein S1, ZINC ION
Authors:Grishkovskaya, I, Byrgazov, K, Moll, I, Djinovic-Carugo, K.
Deposit date:2014-06-05
Release date:2014-12-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for the interaction of protein S1 with the Escherichia coli ribosome.
Nucleic Acids Res., 43, 2015
7PJS
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BU of 7pjs by Molmil
Structure of the 70S ribosome with tRNAs in the classical pre-translocation state and apramycin (C)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N.
Deposit date:2021-08-24
Release date:2021-10-20
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural mechanism of GTPase-powered ribosome-tRNA movement
Nat Commun, 12, 2021
7S1J
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Wild-type Escherichia coli ribosome with antibiotic radezolid
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D.
Deposit date:2021-09-02
Release date:2022-03-02
Method:ELECTRON MICROSCOPY (2.47 Å)
Cite:Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Nat.Struct.Mol.Biol., 29, 2022
7S1I
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Wild-type Escherichia coli stalled ribosome with antibiotic radezolid
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Young, I.D, Stojkovic, V, Tsai, K, Lee, D.J, Fraser, J.S, Galonic Fujimori, D.
Deposit date:2021-09-02
Release date:2022-03-02
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.48 Å)
Cite:Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics.
Nat.Struct.Mol.Biol., 29, 2022
6YSS
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BU of 6yss by Molmil
Structure of the P+9 ArfB-ribosome complex in the post-hydrolysis state
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V.
Deposit date:2020-04-23
Release date:2020-08-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Mechanism of ribosome rescue by alternative ribosome-rescue factor B.
Nat Commun, 11, 2020
7NWT
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Initiated 70S ribosome in complex with 2A protein from encephalomyocarditis virus (EMCV)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Hill, C.H, Napthine, S, Pekarek, L, Kibe, A, Firth, A.E, Graham, S.C, Caliskan, N, Brierley, I.
Deposit date:2021-03-17
Release date:2021-12-15
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.66 Å)
Cite:Structural and molecular basis for Cardiovirus 2A protein as a viral gene expression switch
Nat Commun, 12, 2021
7AF8
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Bacterial 30S ribosomal subunit assembly complex state E (head domain)
Descriptor: 16SrRNA (head domain of the 30S ribosome, 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Fucini, P, Connell, S.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
8EYT
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30S_delta_ksgA+KsgA complex
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Sun, J, Kinman, L.F, Jahagirdar, D, Ortega, J, Davis, J.H.
Deposit date:2022-10-28
Release date:2023-09-06
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Nat.Struct.Mol.Biol., 30, 2023
7M5D
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BU of 7m5d by Molmil
Cryo-EM structure of a non-rotated E.coli 70S ribosome in complex with RF3-GTP, RF1 and P-tRNA (state I)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Zhang, J.
Deposit date:2021-03-23
Release date:2022-10-19
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of a non-rotated E.coli 70S ribosome in complex with RF3-GTP, RF1 and P-tRNA (state I)
To Be Published
7AF3
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Bacterial 30S ribosomal subunit assembly complex state M (head domain)
Descriptor: 16S rRNA (head), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.R.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
6ORE
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Release complex 70S
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Fu, Z.
Deposit date:2019-04-30
Release date:2019-06-19
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:The structural basis for release-factor activation during translation termination revealed by time-resolved cryogenic electron microscopy.
Nat Commun, 10, 2019
7TOS
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BU of 7tos by Molmil
E. coli 70S ribosomes bound with the ALS/FTD-associated dipeptide repeat protein PR20
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A.
Deposit date:2022-01-24
Release date:2022-05-25
Last modified:2024-02-21
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
7AFA
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BU of 7afa by Molmil
Bacterial 30S ribosomal subunit assembly complex state F (head domain)
Descriptor: 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Kaminishi, T, Diercks, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7NAX
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BU of 7nax by Molmil
Complete Bacterial 30S ribosomal subunit assembly complex state I (Consensus Refinement)
Descriptor: 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2021-01-25
Release date:2021-12-08
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7AF5
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BU of 7af5 by Molmil
Bacterial 30S ribosomal subunit assembly complex state I (head domain)
Descriptor: 16SrRNA (head domain of the 30S ribosome), 30S ribosomal protein S10, 30S ribosomal protein S13, ...
Authors:Schedlbauer, A, Iturrioz, I, Ochoa-Lizarralde, B, Diercks, T, Lopez-Alonso, J, Kaminishi, T, Capuni, R, Astigarraga, E, Gil-Carton, D, Fucini, P, Connell, S.
Deposit date:2020-09-19
Release date:2021-07-07
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit.
Sci Adv, 7, 2021
7Q4K
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BU of 7q4k by Molmil
Erythromycin-stalled Escherichia coli 70S ribosome with streptococcal MsrDL nascent chain
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fostier, C.R, Ousalem, F, Soufari, H, Leroy, E.C, Ngo, S, Innis, A, Hashem, Y, Boel, G.
Deposit date:2021-10-31
Release date:2022-11-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Regulation of the macrolide resistance ABC-F translation factor MsrD.
Nat Commun, 14, 2023
6WD0
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BU of 6wd0 by Molmil
Cryo-EM of elongating ribosome with EF-Tu*GTP elucidates tRNA proofreading (Cognate Structure I-A)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Loveland, A.B, Demo, G, Korostelev, A.A.
Deposit date:2020-03-31
Release date:2020-07-01
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading.
Nature, 584, 2020
6ZTP
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BU of 6ztp by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 6
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZTO
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BU of 6zto by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 1
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-20
Release date:2020-09-23
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
6ZU1
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BU of 6zu1 by Molmil
E. coli 70S-RNAP expressome complex in uncoupled state 2
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Webster, M.W, Takacs, M, Weixlbaumer, A.
Deposit date:2020-07-21
Release date:2020-09-16
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of transcription-translation coupling and collision in bacteria.
Science, 369, 2020
8URY
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BU of 8ury by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 30 nt long spacer, and fMet-tRNA in E-site and P-site of the ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ...
Authors:Molodtsov, V, Wang, C, Ebright, R.H.
Deposit date:2023-10-27
Release date:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis of RfaH-mediated transcription-translation coupling
Nat.Struct.Mol.Biol., 2024

 

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