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PDB: 47 results

7NVU
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BU of 7nvu by Molmil
RNA polymerase II core pre-initiation complex with open promoter DNA
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7OOB
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Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA damage-binding protein 1, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-27
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7F4G
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Structure of RPAP2-bound RNA polymerase II
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Chen, X, Qi, Y, Wang, X, Li, J, Zhao, D, Xu, Y.
Deposit date:2021-06-18
Release date:2021-07-07
Last modified:2022-07-20
Method:ELECTRON MICROSCOPY (2.78 Å)
Cite:RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Cell Rep, 39, 2022
7OO3
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Pol II-CSB-CSA-DDB1-UVSSA (Structure1)
Descriptor: CSB element, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-26
Release date:2021-10-06
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7B7U
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BU of 7b7u by Molmil
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Fianu, I, Dienemann, C, Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2020-12-11
Release date:2021-05-19
Last modified:2022-02-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2.
Commun Biol, 4, 2021
8OEW
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BU of 8oew by Molmil
Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure, structure 2)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P.
Deposit date:2023-03-13
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
7NVS
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BU of 7nvs by Molmil
RNA polymerase II core pre-initiation complex with closed promoter DNA in proximal position
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
8OEV
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BU of 8oev by Molmil
Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure, structure 3)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P.
Deposit date:2023-03-13
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
8S52
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RNA polymerase II core initially transcribing complex with an ordered RNA of 10 nt
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
Deposit date:2024-02-22
Release date:2024-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
7OOP
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Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3)
Descriptor: DNA damage-binding protein 1, DNA excision repair protein ERCC-6, DNA excision repair protein ERCC-8, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-28
Release date:2021-10-06
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7NVT
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BU of 7nvt by Molmil
RNA polymerase II core pre-initiation complex with closed promoter DNA in distal position
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Aibara, S, Schilbach, S, Cramer, P.
Deposit date:2021-03-16
Release date:2021-05-05
Last modified:2021-06-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of mammalian RNA polymerase II pre-initiation complexes.
Nature, 594, 2021
7OL0
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BU of 7ol0 by Molmil
Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P.
Deposit date:2021-05-18
Release date:2021-07-14
Last modified:2021-09-01
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
7OPD
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BU of 7opd by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5)
Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-31
Release date:2021-10-06
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7OPC
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BU of 7opc by Molmil
Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4)
Descriptor: Cullin-4A, DNA damage-binding protein 1, DNA excision repair protein ERCC-6, ...
Authors:Kokic, G, Cramer, P.
Deposit date:2021-05-31
Release date:2021-10-13
Last modified:2021-10-27
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of human transcription-DNA repair coupling.
Nature, 598, 2021
7ZWD
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BU of 7zwd by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-19
Release date:2022-11-30
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX8
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BU of 7zx8 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-12-07
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
8A40
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BU of 8a40 by Molmil
Structure of mammalian Pol II-TFIIS elongation complex
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P.
Deposit date:2022-06-09
Release date:2023-08-23
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of a backtracked hexasomal intermediate of nucleosome transcription.
Mol.Cell, 82, 2022
8OEU
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BU of 8oeu by Molmil
Structure of the mammalian Pol II-SPT6 complex (composite structure, Structure 4)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P.
Deposit date:2023-03-13
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.04 Å)
Cite:Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
8OF0
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BU of 8of0 by Molmil
Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Kokic, G, Dienemann, C, Dybkov, O, Urlaub, H, Cramer, P.
Deposit date:2023-03-13
Release date:2023-10-18
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Structure of the transcribing RNA polymerase II-Elongin complex.
Nat.Struct.Mol.Biol., 30, 2023
8S51
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BU of 8s51 by Molmil
RNA polymerase II core initially transcribing complex with an ordered RNA of 8 nt
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Zhan, Y, Grabbe, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
Deposit date:2024-02-22
Release date:2024-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
6TED
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BU of 6ted by Molmil
Structure of complete, activated transcription complex Pol II-DSIF-PAF-SPT6 uncovers allosteric elongation activation by RTF1
Descriptor: DNA (37-MER), DNA-directed RNA polymerase II subunit RPB9, DNA-directed RNA polymerase subunit, ...
Authors:Vos, S.M, Farnung, L, Cramer, P.
Deposit date:2019-11-11
Release date:2020-07-22
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of complete Pol II-DSIF-PAF-SPT6 transcription complex reveals RTF1 allosteric activation.
Nat.Struct.Mol.Biol., 27, 2020
8P4B
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BU of 8p4b by Molmil
Structural insights into human co-transcriptional capping - structure 2
Descriptor: DNA (35-MER), DNA (5'-D(P*AP*GP*CP*GP*GP*CP*GP*GP*AP*GP*CP*CP*AP*GP*CP*AP*GP*GP*GP*AP*GP*CP*TP*G)-3'), DNA-directed RNA polymerase II subunit E, ...
Authors:Garg, G, Dienemann, C, Farnung, L, Schwarz, J, Linden, A, Urlaub, H, Cramer, P.
Deposit date:2023-05-20
Release date:2023-08-16
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into human co-transcriptional capping.
Mol.Cell, 83, 2023
7OKX
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Structure of active transcription elongation complex Pol II-DSIF (SPT5-KOW5)-ELL2-EAF1 (composite structure)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB1, ...
Authors:Chen, Y, Vos, S.M, Dienemann, C, Ninov, M, Urlaub, H, Cramer, P.
Deposit date:2021-05-18
Release date:2021-07-14
Last modified:2021-09-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Allosteric transcription stimulation by RNA polymerase II super elongation complex.
Mol.Cell, 81, 2021
8S54
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BU of 8s54 by Molmil
RNA polymerase II early elongation complex bound to TFIIE and TFIIF - state b (composite structure)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Zhan, Y, Grabber, F, Oberbeckmann, E, Dienemann, C, Cramer, P.
Deposit date:2024-02-22
Release date:2024-04-17
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Three-step mechanism of promoter escape by RNA polymerase II.
Mol.Cell, 84, 2024
7ZX7
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BU of 7zx7 by Molmil
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
Descriptor: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
Authors:Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
Deposit date:2022-05-20
Release date:2022-11-30
Last modified:2022-12-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022

 

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PDB entries from 2024-06-12

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