1EBM
| CRYSTAL STRUCTURE OF THE HUMAN 8-OXOGUANINE GLYCOSYLASE (HOGG1) BOUND TO A SUBSTRATE OLIGONUCLEOTIDE | Descriptor: | 8-OXOGUANINE DNA GLYCOSYLASE, CALCIUM ION, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3'), ... | Authors: | Bruner, S.D, Norman, D.P, Verdine, G.L. | Deposit date: | 2000-01-24 | Release date: | 2000-03-20 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature, 403, 2000
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1FN7
| COUPLING OF DAMAGE RECOGNITION AND CATALYSIS BY A HUMAN BASE-EXCISION DNA REPAIR PROTEIN | Descriptor: | 8-OXOGUANINE DNA GLYCOSYLASE 1, CALCIUM ION, DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*CP*C)-3'), ... | Authors: | Norman, D.P.G, Bruner, S.D, Verdine, G.L. | Deposit date: | 2000-08-21 | Release date: | 2001-04-21 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein. J.Am.Chem.Soc., 123, 2001
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1KO9
| Native Structure of the Human 8-oxoguanine DNA Glycosylase hOGG1 | Descriptor: | 8-oxoguanine DNA glycosylase, SULFATE ION | Authors: | Bjoras, M, Seeberg, E, Luna, L, Pearl, L.H, Barrett, T.E. | Deposit date: | 2001-12-20 | Release date: | 2002-01-09 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Reciprocal "flipping" underlies substrate recognition and catalytic activation by the human 8-oxo-guanine DNA glycosylase. J.Mol.Biol., 317, 2002
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1LWW
| Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-bromoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-BROMOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
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1LWV
| Borohydride-trapped hOgg1 Intermediate Structure Co-Crystallized with 8-aminoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-AMINOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
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1LWY
| hOgg1 Borohydride-Trapped Intermediate without 8-oxoguanine | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE DNA GLYCOSYLASE | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2002-06-03 | Release date: | 2003-02-25 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Product-Assisted Catalysis in Base Excision DNA Repair Nat.Struct.Biol., 10, 2003
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1HU0
| CRYSTAL STRUCTURE OF AN HOGG1-DNA BOROHYDRIDE TRAPPED INTERMEDIATE COMPLEX | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(PED)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 8-OXOGUANINE, ... | Authors: | Fromme, J.C, Bruner, S.D, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2001-01-03 | Release date: | 2003-02-25 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Product-Assisted Catalysis in base-excision DNA Repair Nat.Struct.Biol., 10, 2003
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1N39
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | CALCIUM ION, DNA complement strand, DNA inhibitor strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
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1N3A
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | CALCIUM ION, DNA complement strand, DNA inhibitor strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
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1N3C
| Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase | Descriptor: | 8-oxoG-containing DNA, CALCIUM ION, DNA complement strand, ... | Authors: | Norman, D.P, Chung, S.J, Verdine, G.L. | Deposit date: | 2002-10-25 | Release date: | 2003-03-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biochemical exploration of a critical amino acid in human 8-oxoguanine glycosylase Biochemistry, 42, 2003
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1M3Q
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1M3H
| Crystal Structure of Hogg1 D268E Mutant with Product Oligonucleotide | Descriptor: | 5'-D(P*GP*CP*GP*TP*CP*CP*AP*(DDX))-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*TP*AP*CP*C)-3', ... | Authors: | Chung, S.J, Verdine, G.L. | Deposit date: | 2002-06-27 | Release date: | 2004-04-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structures of End Products Resulting from Lesion Processing by a DNA Glycosylase/Lyase Chem.Biol., 11, 2004
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1YQM
| Catalytically inactive human 8-oxoguanine glycosylase crosslinked to 7-deazaguanine containing DNA | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(7GU)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-02 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
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1YQK
| Human 8-oxoguanine glycosylase crosslinked with guanine containing DNA | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*G)-3', 5'-D(P*CP*AP*GP*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-01 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
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1YQR
| Catalytically inactive human 8-oxoguanine glycosylase crosslinked to oxoG containing DNA | Descriptor: | 5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-02 | Release date: | 2005-04-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
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1YQL
| Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA | Descriptor: | 5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*CP*AP*(PPW)P*GP*TP*CP*TP*AP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Yang, W, Karplus, M, Verdine, G.L. | Deposit date: | 2005-02-02 | Release date: | 2005-04-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of a repair enzyme interrogating undamaged DNA elucidates recognition of damaged DNA. Nature, 434, 2005
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2I5W
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2NOL
| Structure of catalytically inactive human 8-oxoguanine glycosylase distal crosslink to oxoG DNA | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Banerjee, A, Radom, C.T, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOH
| Structure of catalytically inactive Q315A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA | Descriptor: | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOZ
| Structure of Q315F human 8-oxoguanine glycosylase distal crosslink to 8-oxoguanine DNA | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*G*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-26 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOF
| Structure of Q315F human 8-oxoguanine glycosylase proximal crosslink to 8-oxoguanine DNA | Descriptor: | 5'-D(*GP*CP*GP*TP*C*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOI
| Structure of G42A human 8-oxoguanine glycosylase crosslinked to undamaged G-containing DNA | Descriptor: | 5'-D(*GP*CP*GP*TP*C*CP*AP*GP*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOB
| Structure of catalytically inactive H270A human 8-oxoguanine glycosylase crosslinked to 8-oxoguanine DNA | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*T*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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2NOE
| Structure of catalytically inactive G42A human 8-oxoguanine glycosylase complexed to 8-oxoguanine DNA | Descriptor: | 5'-D(*G*CP*GP*TP*CP*CP*AP*(G42)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*G*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', CALCIUM ION, ... | Authors: | Radom, C.T, Banerjee, A, Verdine, G.L. | Deposit date: | 2006-10-25 | Release date: | 2006-11-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural characterization of human 8-oxoguanine DNA glycosylase variants bearing active site mutations. J.Biol.Chem., 282, 2007
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3F0Z
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