1M3Q
Crystal Structure of hogg1 D268E Mutant with Base-Excised DNA and 8-aminoguanine
Summary for 1M3Q
Entry DOI | 10.2210/pdb1m3q/pdb |
Related | 1EBM 1M3H |
Descriptor | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3', 5'-D(*GP*CP*GP*TP*CP*CP*AP*(DRZ)P*GP*TP*CP*TP*AP*CP*C)-3', 8-oxoguanine DNA glycosylase, ... (6 entities in total) |
Functional Keywords | 8-oxoguanine, dna glycosylase, dna repair, end product, hogg, 8-aminoguanine, re-ligation, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus, nucleoplasm. Isoform 1A: Nucleus. Isoform 2A: Mitochondrion: O15527 |
Total number of polymer chains | 3 |
Total formula weight | 44916.40 |
Authors | Chung, S.J.,Verdine, G.L. (deposition date: 2002-06-28, release date: 2004-02-17, Last modification date: 2024-02-14) |
Primary citation | Chung, S.J.,Verdine, G.L. Structures of End Products Resulting from Lesion Processing by a DNA Glycosylase/Lyase Chem.Biol., 11:1643-1649, 2004 Cited by PubMed: 15610848DOI: 10.1016/j.chembiol.2004.09.014 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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