1M3Q
Crystal Structure of hogg1 D268E Mutant with Base-Excised DNA and 8-aminoguanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3' | polymer | 15 | 4635.0 | 1 | |||
| 2 | B (C) | 5'-D(*GP*CP*GP*TP*CP*CP*AP*(DRZ)P*GP*TP*CP*TP*AP*CP*C)-3' | polymer | 15 | 4412.8 | 1 | |||
| 3 | C (A) | 8-oxoguanine DNA glycosylase | polymer | 317 | 35662.3 | 1 | UniProt (O15527) Pfam (PF07934) Pfam (PF00730) | Homo sapiens (human) | |
| 4 | D (C) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E (A) | 8-AMINOGUANINE | non-polymer | 166.1 | 1 | Chemie (ANG) | |||
| 6 | F, G, H (B, C, A) | water | water | 18.0 | 174 | Chemie (HOH) |
Sequence modifications
A: 12 - 325 (UniProt: O15527)
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | cloning artifact |
| Ser 10 | - | cloning artifact |
| Glu 11 | - | cloning artifact |
| Glu 268 | Asp 268 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44710.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 206.2 | |
| All* | Total formula weight | 44916.4 |
